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Showing 1 to 3 of 3 for “"Actinium-225"”.
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Medical Isotope Production of Actinium 225 By Linear Accelerator Photon Irradiation of Radium 226
… present and future need for the medical isotope Actinium-225, currently in short supply worldwide. Only a couple manufacturers produce it in very low quantities. In roughly the past 10 years the medical community has explored the use of Ac-225 and its daughter Bismuth-213 for targeting a number …
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Experimental approaches for the production of thorium-229
… relatively low toxicity to the rest of the body. Actinium-225 is an ideal radioisotope for TAT due to its short half-life (t1/2=9.92 days) and 3 α-emitting decay daughters. Currently, there is not enough 225Ac available to meet expected demand. Therefore, the goal of this research is to produce …
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Development and Evaluation of Novel Anti-HER2 Theranostics Against HER2-Positive Breast Cancer
… imaging. We also radiolabeled these ADCs with [225Ac]Ac via a stable eighteen-membered macrocyclic chelator p-SCN-Macropa for alpha particle therapy. All immunoconjugates were characterized using size exclusion high performance liquid chromatography (SEC-HPLC), flow cytometry, and antibody …