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Showing 1 to 11 of 11 for “"Acid-base reactions"”.
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STUDENTS’ UNDERSTANDINGS OF ACID-BASE REACTIONS INVESTIGATED THROUGH THEIR CLASSIFICATION SCHEMES AND THE ACID-BASE REACTIONS CONCEPT INVENTORY
Acid base reactions are an important part of the curriculum in many chemistry courses. Students’ knowledge about acid-base reactions is dependent on their ability to transfer knowledge from multiple topics such as solutions, reaction chemistry, and structure/property relationships, making it a ripe …
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ACID-BASE REACTIONS IN DIFFERENT SOLID-STATE FORMS
… drug substances are reported to be either weak acids or weak bases. Hence, acid-base reactions are commonly observed in pharmaceutical systems with samples including salts, amorphous solid dispersions, and in formulated products. Salt formation of active pharmaceutical ingredients (APIs) is …
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Photometric studies of non-aqueous acid-base reactions
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1959.
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Pushing the Limits of the Lithium Indicator Carbon Acidity Scale Using Cyclopentadiene Chemistry and 19F NMR Spectrometry
… of ordinary chemical bond and studying carbon acidity will help us understand and predict the reactivity of organic compounds. Carbon acidities are ranked using acidity scales. One of the most prominent is the Streitwieser Lithium Indicator (SLI) scale. The term "indicator scale" implies that …
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An Improved MUSIC Model for Gibbsite
… routines. We also estimated pKa values for acid/base reactions at gibbsite surfaces by applying a new bond-valence method to gibbsite (001)-type and (100)-type surface structures based on <em>ab initio</em> calculations. The resulting pKa estimates are not to be taken as precise values due …
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The interaction of metal ions at the hydrous manganese dioxide-solution interface
… to the surface charge that originates because of acid-base reactions at the surface. The surface charge is pH dependent, and the pH of zero point of charge for the hydrous manganese dioxide used in this study was 2.25. The surface charge increases rapidly for pH values greater than the pH of zero …
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Two-Part Reactive Formulations for Intranasal Delivery of Benzodiazepines
… we describe how a prodrug/enzyme reaction or an acid/base reaction can be used to deliver a benzodiazepine in an aqueous vehicle with a volume and pH appropriate for intranasal administration. When the soluble components of these two-part reactive formulations are mixed at the time of …
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Applications development of broadband acoustic resonance dissolution spectroscopy (BARDS) in the pharmaceutical, food and animal nutrition industries
… tablets and a myriad of formulations. It is based on a phenomenon which occurs during the dissolution of solid material in solution. When the sample is added the solution undergoes changes in its compressibility due to gas evolution in solution. This has the effect of slowing down a resonant …
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Expanding the chemistry of a cupredoxin by designing nonnative active sites and using abiological metals
… oxidative or reductive transformations, acid-base reactions, and maintaining protein structural stability. Copper is found in both electron transfer proteins, most notably cupredoxins, and enzymes that catalyze oxidative reactions, such as copper-dependent monooxygenases. Cupredoxins are …
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Characterisation of drug loaded insoluble polymeric matrices prepared by hot melt extrusion technology for drug delivery applications.
… and drug release properties evaluated. The free base (QB), hydrochloride (QHC1) and sulphate (QSO4) forms were selected and formulated with Eudragit" RL PO. The free base form exhibited the highest saturation solubility within the matrix at 28.48 ± 3.4 % w/w, QS04 19.27 ± 2.34% w/w and the …