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Showing 1 to 19 of 19 for “"Acetylsalicylic acid"”.
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DEVELOPMENT OF A NEW CONTROLLED RELEASE DOSAGE FORM OF ACETYLSALICYLIC ACID
The pharmaceutical agent, acetylsalicylic acid (ASA) is commonly used in the treatment of rheumatoid arthritis. However, due to the gastrointestinal injury caused by the ASA, it is recommended that patients who must take ASA regularly, use enteric coated ASA. Additionally, the short half-life of …
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Quantitative Analysis of Acetylsalicylic Acid by q-NMR (Quantitative-Nuclear Magnetic Resonance Spectroscopy)
… magnetic resonance spectroscopy (q-NMR) of acetylsalicylic acid (ASA) was conducted using <em>tert</em>-butyl alcohol (<em>tert</em>-butanol) as the internal standard and deuterated chloroform (CDCl<sub>3</sub>) as the solvent. Preparations of ASA solutions in low and high concentration …
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Effects of acetylsalicylic acid on odontogenesis of human dental pulp cells and TGF-ß1 liberation from dentin
Acetylsalicylic acid (ASA), aspirin, is a renowned NSAID that its role in the process of bone metabolism has recently come to light. However, the influence of ASA on the odontogenesis of human dental pulp cells (HDPCs) remains elusive. In search of materials that would synergize the healing …
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Modification of aspirin derivatives by coordination to iron and manganese
In this work new metal complexes of acetylsalicylic acid (aspirin) derivatives have been synthesised. Complexes that were studied were those of manganese (Mn) and iron (Fe).
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Quantitative Determination of Acetylsalicyclic Acid and Acetaminophen by Q-NMR (Quantitative Nuclear Magnetic Resonance) Technique
… (quantitative NMR) to quantitatively analyze acetylsalicylic acid and acetaminophen by Proton-NMR using diethyl ether as an internal standard. The area of NMR signals shows a linear relationship with the concentration. Acetylsalicylic acid and acetaminophen were chosen as a representative …
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ΜΕΛΕΤΗ ΤΗΣ ΒΙΟΙΣΟΔΥΝΑΜΙΑΣ ΙΔΙΟΣΚΕΥΑΣΜΑΤΩΝ ΑΣΠΙΡΙΝΗΣ ΠΟΥ ΚΥΚΛΟΦΟΡΟΥΝ ΣΤΗΝ ΕΛΛΑΔΑ
… OF ORALLY ADMINISTERED PRODUCTS CONTAINING ACETYLSALICYLIC ACID WAS STUDIED IN HUMAN VOLUNTEERS. THE ADMINISTERED DRUGS, EACH OF WHICH CONTAINED 500 MG OF THE ACTIVE SUBSTANCE WERE THE FOLLOWING ASPIRIN R, COLFORT R, SALOSPIR R, NASPIN K, KALACALINE R AND CESPIRE R. THE PHARMACOKINETIC …
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Acing nucleic acids and chemistry : exogenous RNA/DNA acetylation and modeling universal data formats.
… of three different pharmacons, acetic anhydride, acetylsalicylic acid, and sulfo-NHS acetate, to acetylate RNA and DNA. I then aim to determine the rate of the amide proton-solvent exchange rate of acetylated nucleic acids. Amide hydrogen/deuterium exchange has been studied on proteins for decades …
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SNARE specificity in membrane protein traffic
… and localisation of KAT1 in tobacco cells. Acetylsalicylic acid was also used to combat the effects of the wound response activated during slide preparation. Coexpression of KAT1 with SYP121-Sp2, SYP122-Sp2 and SYP71-Sp2 resulted in a disruption of trafficking and in microdomains becoming …
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Uso do ácido acetilsalicílico na prevenção de doenças cardiovasculares.
… the prevention of these diseases and the use of acetylsalicylic acid (ASA) is one such measure. The present work aims to compile updated information on the adoption of pharmacological therapy of aspirin in primary prevention standpoint and / or secondary CVD. The sources used for the development …
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Pollutant monitoring with fibre optics in the deep ultraviolet
… low concentrations of nitrates, chlorine and acetylsalicylic acid.
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Significant Association of IL-18 Genetic Polymorphisms with Aspirin-Intolerant Urticaria in a Korean Population
INTRODUCTION: Aspirin(acetylsalicylic acid)-intolerant urticaria(AIU) aggravates urticaria after aspirin ingestion. Although the pathogenesis of AIU has not been fully understood, mast cell activation and neutrophil infiltration have been suggested to be involved. Interleukin-18 (IL-18) can …
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Controlled Release System for Localized and Sustained Drug Delivery Applications
… stability and dissolution of the system in acidic media. In the present study, chitosan microparticles were prepared by emulsification process. The model drug chosen was acetylsalicylic acid as it is a small and challenging molecule. The maximum loading capacity obtained for the …
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Effects of several abiotic and biotic factors and plant hormones on growth, morophology, and camptothecin accumulation in Camptotheca acuminata seedlings
… and ultraviolet (UV) light], biotic factor [acetylsalicylic acid (ASA)], and plant hormones [benzyl adenine (BA) and naphthalene acetic acid (NAA)] on growth, morphology, and secondary metabolite, camptothecin (CPT, an anti-cancer compound) accumulation in Camptotheca acuminata. Five …
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Role of Cyclooxygenase Isoforms in Peripheral Neuropathic Pain Model
… the mechanical hyperalgesia, however acetylsalicylic acid (5 mg/kg), a preferential COX-1 inhibitor did not significantly alleviate them. COX- isoforms mRNA and COX protein in the dorsal root ganglia (DRG), entering sensory information into the spinal cord were significantly increased. …
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Genetic effect of histamine N-methyltransferase (HNMT) polymorphism on chronic urticaria with aspirin hypersensitivity
… AND OBJECTIVE: The pathogenic mechanism of ASA (acetylsalicylic acid)-induced urticaria is still poorly understood, but it has been known that released histamine by cutaneous mast cell activation is considered to be an important role. Biogenic histamine levels are regulated by histamine synthesis …
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A structural systematic study of three families of salicyclic acid derivatives
… thesis three families of substituted salicylic acid derivatives have been prepared and separately studied in order to compare the crystal structures and determine whether the substitution and the associated changes in shape and electrostatic of the parent molecule introduce alternative …
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Long Term Outcome and Prediction Models of Cognition, Activities of Daily Living and Nursing Home Placement in Alzheimer’s Disease with Cholinesterase Inhibitor Treatment
… absence of the APOE ε4 allele or usage of NSAIDs/acetylsalicylic acid were predictors of improved cognitive response to ChEI treatment after 6 months, and of a more positive long-term outcome. III. Lower cognitive status at baseline, older age, higher education level, and solitary living were …
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Primary sclerosing cholangitis: from genetic risk to disease biology
… is already targeted by proteasome inhibitors and acetylsalicylic acid, both of which could be potentially therapeutic in PSC. PSC is a debilitating disease with serious disease sequelae, for which new therapeutic options are urgently needed. In this thesis, I elucidate multiple genes with a causal …