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Showing 1 to 3 of 3 for “"Accelerated study"”.
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Development of a Kinetic Model to Investigate the Effect of Compositional Variation and a Processing Condition on the Solid-State Degradation of Gabapentin
… excipients were prepared and stored under accelerated study conditions. The concentration of lactam and gabapentin was measured using a validated analytical method. A concentration dependent catalytic effect by the excipients was determined by mixing different concentrations of the …
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A 'Biorelevant' Approach for Accelerated In Vitro Release and In Vitro-In Vivo Relationship of a Biodegradable, Naltrexone Implant
… long acting delivery system for naltrexone. Accelerated in vitro methods are also important for quality assurance of manufactured dosage forms. For drug release testing of sustained release parenteral dosage forms, the modified USP Apparatus 4 (flow-through cell) has been recommended by the …
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Development of the Sustained Release Analgesic Formulations for Rodents and a Novel In Vitro Model for Parenteral Formulations with the Character of a Level A IVIVC
… Therefore, the second objective of this study was to (1) design and develop a new dissolution model with the character of Level A IVIVC for oily formulations, and (2) develop a mathematical equation to describe the drug release mechanism from the in vitro model. In general, it is accepted …