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Showing 1 to 4 of 4 for “"Acanthamoeba Keratitis"”.
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Acanthamoeba spp. Secrete a Mannose-Induced Protein that Correlates with Ability to Cause Acanthamoeba Keratitis
Acanthamoeba spp. are ubiquitously distributed in the environment. The trophozoite form can infect the cornea and cause sight-threatening corneal inflammation known as Acanthamoeba keratitis. The pathogenic cascade of Acanthamoeba keratitis begins when Acanthamoebae bind to mannose expressed on …
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Establishing an ex vivo model of acanthamoeba keratitis and investigating the phenotypic similarities between the protozoan acanthamoeba and human macrophages
Acanthamoeba is a small free-living amoeba found in tap water and soil with two life stages: the trophozoite and cyst. Acanthamoeba species are opportunistic pathogens of humans that cause two main diseases including a potentially blinding infection of the cornea called Acanthamoeba keratitis (AK) …
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Comparative efficacy of azole compounds targeting sterol 14-demethylase against multiple isolates of Acanthamoeba castellanii and polyphaga
The species of the genus Acanthamoeba are normally free-living protozoan parasites, found ubiquitously in the environment. However, they are also have the ability to parasitise humans where they cause a variety of diseases depending upon the anatomical site of infection and the immune status of the …
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Developing novel therapeutic agents for Acanthamoeba infection and investigating the process of encystment
Acanthamoeba Keratitis (AK) is a vision-threatening disease which can lead to blinding corneal tissue infection. Many patients who have been infected with Acanthamoeba in their eye do not respond to the current medical treatments involving polyhexamethylene biguanide or chlorhexidine despite the in …