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Showing 1 to 20 of 34 for “"Acanthamoeba"”.
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Adhesion mechanisms of Acanthamoeba
Made available in DSpace on 2011-05-07T12:30:25Z (GMT). No. of bitstreams: 2 license.txt: 4922 bytes, checksum: 910b249b4beec47e7ab768910c8f966f (MD5) 9136679.pdf: 3507094 bytes, checksum: d9f1d897d82836c6484f182b3a2c4edb (MD5) Previous issue date: 1991
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Acanthamoeba spp. Secrete a Mannose-Induced Protein that Correlates with Ability to Cause Acanthamoeba Keratitis
Acanthamoeba spp. are ubiquitously distributed in the environment. The trophozoite form can infect the cornea and cause sight-threatening corneal inflammation known as Acanthamoeba keratitis. The pathogenic cascade of Acanthamoeba keratitis begins when Acanthamoebae bind to mannose expressed on …
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Establishing an ex vivo model of acanthamoeba keratitis and investigating the phenotypic similarities between the protozoan acanthamoeba and human macrophages
Acanthamoeba is a small free-living amoeba found in tap water and soil with two life stages: the trophozoite and cyst. Acanthamoeba species are opportunistic pathogens of humans that cause two main diseases including a potentially blinding infection of the cornea called Acanthamoeba keratitis (AK) …
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Purification and characterization of TFIIIA from Acanthamoeba castellanii
Our interest has been in studying the mechanisms of RNA polymerase III (Pol III) transcription and the regulation of this process in A. castellanii, which was specifically focused on TFIIIA. This factor only activates Pol Ill-mediated transcription from 5S RNA genes and is the first of three …
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Presence and Role of Acanthamoeba in Wound Infections
… quite common. Free Living Amoebae (FLA), such as Acanthamoeba, are widely distributed in the environment and may also contaminate wounds. It is well known that Acanthamoeba feed on and protect bacteria. The role of Acanthamoeba in wound infections is not very well understood. It is possible that …
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Mechanisms associated with Staphylococcus aureus and Acanthamoeba Interactions, and Therapeutic applications"
… microorganisms such as the free-living amoebae Acanthamoeba which acts as a host for various pathogens. This interaction is highly complex and may be beneficial to one of them or both. The main aims of this project were to study the interactions of Acanthamoeba castellanii with …
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DETECTION OF SECRETED PROTEASES AND A MEMBRANE PROTEASE IN PATHOGENIC ACANTHAMOEBA CULBERTSONI
Acanthamoeba culbertsoni (A. culbertsoni) is an amphizoic amoeba that is the causative agent of Granulomatous Amoebic Encephalitis (GAE), an often fatal central nervous system infection that is seen most frequently in severely immunocompromised patients and is characterized by hemorrhagic and …
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Microbial Ecology of Acanthamoeba polyphaga and Sulfate-Reducing Bacteria in Premise Plumbing
… process still cause illnesses in the population. Acanthamoebae are ubiquitous in the environment and are resistant to commonly used disinfection methods. In addition to being pathogenic on their own, Acanthamoeba spp. are capable of acting as a host to pathogenic bacteria in potable water. The …
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Developing novel therapeutic agents for Acanthamoeba infection and investigating the process of encystment
Acanthamoeba Keratitis (AK) is a vision-threatening disease which can lead to blinding corneal tissue infection. Many patients who have been infected with Acanthamoeba in their eye do not respond to the current medical treatments involving polyhexamethylene biguanide or chlorhexidine despite the in …
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Microbiology and cell biology of the interaction between Listeria monocytogenes and Acanthamoeba spp.
… interaction of L. monocytogenes with freeliving Acanthamoeba spp. and the impact of plasmid-associated genes on their interaction were investigated. Several strains of environmental and clinical isolates of L. monocytogenes were used for co-culture with amoebae. Axenic amoebae were isolated from …
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Role of extended spectrum beta lactamases producing E. coli and Acanthamoeba in urinary tract infections
… and multiply inside the protozoan parasite, Acanthamoeba. The indiscriminate use of various antimicrobial drugs has resulted in the development of drug resistance. Therefore, looking for new or additional antimicrobial compounds is urgent. Four clinical strains of E. coli (three ESBL+ve (TEM, …
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Comparative efficacy of azole compounds targeting sterol 14-demethylase against multiple isolates of Acanthamoeba castellanii and polyphaga
The species of the genus Acanthamoeba are normally free-living protozoan parasites, found ubiquitously in the environment. However, they are also have the ability to parasitise humans where they cause a variety of diseases depending upon the anatomical site of infection and the immune status of the …
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An investigation of the effects of an antimicrobial peptide on the survival of Acanthamoeba and intracellular bacteria associated with Cystic Fibrosis
… also contaminate CF lung. It is well known that Acanthamoeba feed on and protect bacteria. The role of Acanthamoeba in CF lung infections has not yet been investigated. It is possible that the presence of Acanthamoeba in CF lung is one of the key factors for such re-infections. In this study, …
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Experimental Studies on the Microbiota associated with Urinary Tract Infections
… issue relates to the ubiquitous protozoa, Acanthamoeba. Although it is known to cause infections in humans, the amoeba has been isolated from apparently healthy people. Furthermore, Acanthamoeba is known to have an endosymbiotic relationship with bacteria. Therefore, it is reasonable to …
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Cannabinoid Modulation of Chemotaxis of Macrophages and Macrophage-like Cells
… Normal T-cell Expressed and Secreted) and to Acanthamoeba conditioned medium containing secreted proteases. The partial agonist delta-9-tetrahydrocannabinol (THC), administered in vitro, inhibited the chemotactic response of peritoneal macrophages to the chemokine RANTES and to Acanthamoeba …
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Fully automated computer system for diagnosis of corneal diseases. Development of image processing technologies for the diagnosis of Acanthamoeba and Fusarium diseases in confocal microscopy images
… demonstrated its value in the diagnosis of Acanthamoeba and fungal keratitis which considered sight-threatening corneal diseases. However, it can be difficult to find and train confocal microscopy graders to accurately detect Acanthamoeba cysts and fungal filaments in the images. Use of an …
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Fully automated computer system for diagnosis of corneal diseases. Development of image processing technologies for the diagnosis of Acanthamoeba and Fusarium diseases in confocal microscopy images
… demonstrated its value in the diagnosis of Acanthamoeba and fungal keratitis which considered sight-threatening corneal diseases. However, it can be difficult to find and train confocal microscopy graders to accurately detect Acanthamoeba cysts and fungal filaments in the images. Use of an …
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Critical factors controlling regrowth of opportunistic pathogens in premise plumbing
… pneumophila, Mycobacterium avium complex, Acanthamoeba polyphaga, Pseudomonas aeruginosa) residing in human-made water systems, particularly premise plumbing, are now the primary source of water-borne disease in developed countries. The prevention and control of opportunistic pathogens is a …
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An assessment of health hazards associated with the use of water mist systems as a cooling intervention in Australia
… Pseudomonas aeruginosa, Mycobacterium avium, Acanthamoeba and Naegleria fowleri is emerging as a challenge for public health and water quality management. Contrary to other premise plumbing features like showers and domestic taps that have been implicated in various waterborne infections, the …
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Acanthamoebal surface properties and the modulation of phagocytosis
The surface nature of Acanthamoeba trophozoites and cysts was investigated with respect to cell surface charge, hydrophobicity and surface carbohydrate composition. Particulate microelectrophoresis revealed a marked negative charge for both morphological forms, though less for cyst surfaces. …
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