Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Acamprosate"”.
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EFFECTS OF ALCOHOL AND ACAMPROSATE, AN ALCOHOL USE DISORDER TREATMENT, ON NONHUMAN PRIMATE BEHAVIOR AND MEMORY
… drugs are used in the treatment of AUD, with acamprosate being one of the most commonly prescribed drugs. The specific mechanism of acamprosate has not been identified, but it is thought to have an indirect effect on mGluR, NMDA, and possibly GABAA receptors via calcium. This effect is thought …
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Preclinical investigations of GlyT-1 inhibition as a new concept for treatment of alcohol dependence
… Org24598, and compared the effect to that of acamprosate. In summary, the results propose that the GlyT-1 blocker Org25935 increases and stabilizes extracellular glycine levels which, via the GlyR, elevate and preserve a steady dopamine level, which in turn prevents additional ethanol-mediated …