Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Abraxane"”.
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Targeting Breast Cancer With Bacteriophage Associated Silicon Particles
… treatment of breast tumor bearing mice with Abraxane loaded CRKL targeted BASP showed significantly reduced tumor growth in comparison to Abraxane or Abraxane loaded S1MP controls. Overall, this study demonstrates a simple and efficient strategy to target S1MP to breast cancer while …
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Paclitaxel nanoparticles for breast cancer therapy in pregnancy
… or paclitaxel dissolved in Cremophor-EL; Abraxane, an albumin nanoparticle; and Genexol-PM, a polymeric micelle. Using the ex vivo dually perfused human placental cotyledon, we were able to show that paclitaxel transfer appears to be similar across the formulations, but the maternal …
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NOVEL SYNTHETIC PROCESSES FOR THE INDUSTRIAL PREPARATION OF ACTIVE PHARMACEUTICAL INGREDIENTS
… to other conventional formulations of PTX like Abraxane and Cremophor-EL. In order to have an easily scalable process and a final product with high purity a novel synthetic strategy was developed. The second part of the project focused on the development of a process for the industrial …
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Single cell and spatial analysis characterize metabolic DPEP1+ fibroblasts in PDAC
… involving a Hedgehog inhibitor, Gemcitabine/Abraxane, and anti-CTLA4 can reprogram DPEP1<sup>+</sup>CAFs in the PDAC TME. Our study presents a high-resolution atlas of PDAC TME and highlights DPEP1<sup>+</sup>CAFs as a novel CAF subtype critical for PDAC progression and susceptibility to KRAS …