Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Aberrant Crypt Foci"”.
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Impact of Adiposity Status on the Association of Regular Statin Use and Increased Number of Aberrant Crypt Foci
… recent reports suggesting an increased risk of aberrant crypt foci and adenoma. We hypothesize that insufficient control of confounding due to indication bias for prescribing of statins, particularly obesity-induced physiologic dysregulation, might partly explain discrepant results. …
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Effect Of Dietary Folate Restriction On Colon Carcinogenesis In Dna Polymerase β Haploinsufficient Mice
… (FD) resulted in a significant increase in aberrant crypt foci (ACF) formation and triggered liver tumorogenesis in wildtype (WT) animals, as did a BER deficiency in DNA polymerase Β haploinsufficient (Β-pol+/-) mice exposed to 1, 2-dimethylhydrazine (DMH), a known colon and liver …
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Grape Seed Extract as an Adjunct for Modulating Colon Carcinogenesis
… rats. These pre-neoplastic lesions are termed aberrant crypt foci (ACF). Both ACF and ACF with multiplicity (ACF with four or more aberrant crypts within a focus) are putative pre-neoplastic lesions with the potential for development into colonic adenomas or carcinomas. Utilizing three dietary …
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The Effects of Time-Restricted Feeding on Early Phases of Liver and Colon Carcinogenesis
… form (GSTP)-positive lesions in the liver or aberrant crypt foci in the colon. Furthermore, TRF did not mitigate hepatic steatosis, a suspected driver of liver carcinogenesis in high-fat diet conditions, highlighting the persistence of metabolic dysfunction despite meal timing interventions. …
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Epigenetic modifications on WNT genes by dietary genistein during colon cancer development
… colon was collected 6 wk later for evaluation of aberrant crypt foci (ACF), gene expression, and nuclear protein accumulation. AOM injection induced aberrant nuclear accumulation of β-catenin in the CTL but not in the SPI or GEN groups. Moreover, WNT target genes Cyclin D1 and c-Myc were repressed …
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Anti-inflammatory and anti-colon cancer potential of yerba mate (Ilex paraguariensis St. Hilaire) bioactive constituents
… the development of colon pre-neoplastic lesions, aberrant crypt foci (ACF), in the azoxymethane (AOM)-induced model using male F344 rats. The animals received a basal diet and a mate aqueous extract (2% w/v) as drinking fluid, or mate saponins (0.01%, w/w) mixed with the basal diet 2 weeks before …
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The effect of generational feeding of soy and genistein-supplemented diets on progression of precancerous lesions in colon of second generation male rats
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