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Showing 1 to 16 of 16 for “"Abdominal Aortic Aneurysms"”.
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THE ROLE OF CAVEOLAE IN THE FORMATION OF ABDOMINAL AORTIC ANEURYSMS
Abdominal aortic aneurysm (AAA) is a major cardiovascular disease and involves enhancement of renin-angiotensin system and recruitment/activation of inflammatory factors such as matrix metalloproteases (MMP's). Caveolae has been shown to play a role in a number of different cardiovascular diseases …
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Advanced computer modeling of abdominal aortic aneurysms to predict risk of rupture
An abdominal aortic aneurysm (AAA) is an abnormal enlargement of the aorta which is related to weakness of the vessel wall (associated with degradation of connective tissue), and if left untreated will lead to rupture and cause death in 78% to 94% of cases. Approximately 7,000 deaths each year in …
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Transcriptomic Analysis for the Identification and Prioritization of Treatment of Abdominal Aortic Aneurysms
Abdominal aortic aneurysms are pathological dilations of the abdominal aorta, characterized by a high mortality rate, and a lack of effective prognostic predictors. As the disease progresses, the aortic wall becomes significantly degraded and eventually the structure is compromised, leading to …
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Computational model of intraluminal thrombus growth in abdominal aortic aneurysms with fibrin generation
Abdominal aortic aneurysms affect 0.2% of the population and are closely associated with intraluminal thromboses (ILTs) that develop in the sac. Advanced imaging and treatment techniques are available, however there is room for improvement in the methods used to predict the outcome or necessity of …
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The Role of Autophagy in the Pathogenesis and Clinical Course of Abdominal Aortic Aneurysms
Abdominal aortic aneurysm (AAA) is a permanent progressive focal dilation of the aorta that is â Ľ 50% of the normal aortic diameter, due to loss of wall structural integrity. A fatal outcome of the progressive dilation due to the compromised aortic wall integrity is rupture. Mortality associated …
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The fate of proximally excluded iliac arteries following open repair of abdominal aortic aneurysms
Aneurysms occur throughout the length of the aorta, with a large proportion occurring in the infra-renal segment of the abdominal aorta (least 9 to 10 times more common than thoracic aortic aneurysms). Aneurysmal disease of the aorto-iliac segment which commonly occurs as a result of a degenerative …
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Abdominal aortic aneurysms : identification by self-examination and analysis of variation in matrix metalloproteinases with peak wall stress
Abdominal aortic aneurysms (AAAs) cause 5,000 deaths a year in the UK. Self-examination for AAAs may provide an economic and practical solution. Matrix metalloproteinase (MMP) concentration is elevated and levels of their natural inhibitors - Tissue Inhibitors of Matrix Metalloproteinases (TIMPs) …
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Towards An Understanding Of The Etiology Of Abdominal Aortic Aneurysms: Identification Of Genes Implicated In Aaa Risk And Development
<p>Abdominal aortic aneurysm (AAA) is a common disease for which mechanisms of formation are still not well understood. Despite a strong genetic component to AAA risk, specific risk alleles are still largely unidentified. AAA is also a localized disease with a majority occurring in the infrarenal …
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Development and Validation of Non-Invasive Methods for the Identification of Patient-Specific Hyperelastic and Anisotropic Material Properties of Abdominal Aortic Aneurysms In Vivo
An abdominal aortic aneurysm (AAA) is a permanent local dilatation of the human abdominal aorta, posing a severe health risk due to a rupture related mortality rate of up to 85 percent. Current clinical risk assessment relies on a population derived threshold value for the maximum aneurysm …
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Missed opportunities for the detection of abdominal aortic aneurysms : a retrospective study of eighteen patients presenting with a ruptured or acute symptomatic abdominal aortic aneurysm
A ruptured abdominal aortic aneurysm (AAA) has a mortality of 80 percent. The majority of these cases present as medical emergencies, with 50 percent dying before they reach hospital. Twenty percent are not operated on because of an incorrect diagnosis and of the surviving 30 percent, there will be …
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Novel molecular imaging of cardiovascular disease in man
… myocardial infarction or stroke, or rupture of abdominal aortic aneurysms. Conventional imaging modalities have consistently failed to identify atherosclerotic plaques or aneurysms with high-risk pathological features that are at highest risk of rupture or progression. The development of modern …
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Pilvinės aortos aneurizmos automatinės detekcijos nauda matuojant aneurizmos tūrį. Literatūros apžvalga ir modelio sukūrimas /
For almost 20 years, aortic diameter has been the main parameter used not only for diagnosing aortic aneurysms, but also for surveillance, clinical decision-making and follow-ups after interventions. Despite its widespread use, diameter measurement has some relevant limitations. Therefore, aortic …
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Peripheral Arterial Disease from Aetiology to Surgical Management
… focused on aneurysmal disease, specifically, abdominal aortic aneurysms (AAA), the clinical impact of which has had a bearing on the introduction of a National AAA Screening Program in Wales in 2013.<br/><br/>I conclude these sections with a collection of papers that reflect my long term …
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The Soluble Form of the Axl Receptor Tyrosine Kinase
… In the second study, a number of patients with abdominal aortic aneurysms are investigated with Gas6 and sAxl ELISAs to widen our understanding of the Gas6-Axl system. In the patients, Gas6 is increased and sAxl is decreased in the patient group. Aneurysm size correlated to Gas6 concentration …
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A retrospective audit into the morbidity and mortality of open abdominal aortic aneurysm repair at Groote Schuur Hospital, Cape Town
… repairs is 4-8%. Many patients presenting with abdominal aortic aneurysms are elderly and have pre-existing medical conditions, therefore putting them at high risk for numerous post-operative complications, such as acute kidney injury, pulmonary and cardiac complications. These complications …
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Computational Modelling and Treatment Optimization of Acute Endovascular and Respiratory Conditions
… the Coronavirus disease 2019 (COVID-19), and (2) Abdominal Aortic Aneurysms (AAA). In light of the recent COVID-19 pandemic, a low-cost, rapidly deployable emergency ventilator design using a novel fluidic oscillator was developed. The design addresses potential ventilator shortages resulting from …