Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"AV1451"”.
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The role of tau and neuroinflammation in Progressive Supranuclear Palsy and Alzheimer's Disease
… assess the utility of the PET radiotracers [18F]AV1451 and [11C](R)-PK11195 to compare the distribution and intensity of tau pathology and neuroinflammation respectively, in PSP and AD. I use both in vivo scanning and post mortem tissue from archival cases in the Cambridge Brain Bank. For the in …
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The Impact of Traumatic Brain Injury on Neuropsychological Functioning and Tau Accumulation Later in Life in Military Veterans
… 19 in the non-TBI group participated inPET 18F-AV1451 imaging to compare Braak regions. The Mann-Whitney U test was used for analysis of neuropsychological tests (Clock score, BNT, TMT-A, & TMT-B). T-test was used for analysis of neuropsychological test category fluency animals and one-way ANOVA …
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Synaptic loss in the primary tauopathies of Progressive Supranuclear Palsy and Corticobasal Degeneration
… PET, and molecular pathology with [18F]AV1451 PET. Brain structural changes are quantified by MRI. Disease severity and cognition are assessed with the PSP rating scale, and neuropsychological tests. Patients with CBD are negative on amyloid-imaging ([11C]PiB PET) to exclude those with …
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Positron emission tomography in vivo characterisation of the pathology of frontotemporal dementia
Frontotemporal dementia (FTD) is clinically and pathologically diverse, encompassing the behavioural variant FTD; non-fluent variant primary progressive aphasia; and semantic variant primary progressive aphasia. These are usually associated with either tau or TDP-43 pathology, with highly variable …