Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 58 for “"AUD"”.
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The effects of chronic intermittent ethanol exposure on fear conditioning in rats: an investigation of the comorbidity of PTSD and AUD
… anxiety disorders and alcohol use disorder (AUD). Post-traumatic stress disorder (PTSD) and AUD are two such disorders which express extremely high rates of comorbidity that results in a worsened prognosis for each. Despite the high rates of each of these disorders, little is known about the …
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Genetic analysis of bipolar disorder and alcohol use disorder
… prevalence of 1.4% and alcohol use disorder (AUD) a lifetime prevalence of 30.3%, and they are frequently comorbid. Both of these disorders have a relatively high heritability, yet the exact genetic basis of each remains unknown. Genetic variants within the hypothalamic-pituitary-adrenal …
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Investigating Endocannabinoid Metabolism in Alcohol Use Disorder: a focus on fatty acid amide hydrolase (FAAH)
… a therapeutic target for Alcohol Use Disorder (AUD) and psychiatric illnesses. Studies suggest that FAAH regulates alcohol intake/preference, and its impairment increases risk for alcohol use disorder (AUD). This thesis’ main objective was to better characterize the status of FAAH in relation to …
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Preclinical Investigations Of Genetic Correlates Of Alcohol Use Disorder
Alcohol use disorder (AUD) is a common neuropsychiatric condition characterized by uncontrolled alcohol use that has serious medical and social consequences. AUD is heritable and intense work has been done to characterize its genetic basis. Preclinical studies have been critical in describing the …
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Univariate and Multivariate fMRI Investigations of Delay Discounting and Episodic Future Thinking in Alcohol Use Disorder
Alcohol use disorder (AUD) remains a major public health concern globally with substantially increased mortality and a significant economic burden. The low rates of treatment and the high rates of relapse mean that excessive alcohol consumption detrimentally affects many aspects of the user's life …
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Assessment of Ethanol and Nicotine Interactions in the Rat Model: Pharmacotherapeutics, Adolescence, and the Mesolimbic System
Alcohol use disorder (AUD) and nicotine dependence often result in serious health problems and are top contributors to preventable deaths worldwide. Co-addiction to alcohol and nicotine is the most common form of polysubstance abuse. Epidemiological studies indicate that more than 80% of …
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Estimating provisional causal treatment effects on reoffending for binary and multiple treatments using quasi-experimental methods for people in prison with an alcohol use disorder in England
… people in prison with an alcohol use disorder (AUD) to reduce reoffending. Prison-based treatment aims to provide pharmacological and psychosocial interventions that address physical and mental health needs concurrently with approaches to deal with recidivism. This thesis determines whether …
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EFFECTS OF ALCOHOL ABSTINENCE ON CRAVING, STRESS, AND NEUROBIOLOGICAL FUNCTIONING IN MODERATE TO HEAVY ALCOHOL CONSUMERS
… to transitioning from controlled drinking to AUD. Indeed, the majority of research to date has focused on alcohol dependen¬cy. Much less work has focused on a lifestyle including regular alcohol use without a history of AUD. The goal of this dissertation was to provide a step forward in the …
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Towards effective, culturally adapted treatment programs for alcohol service users in Uganda
… In Uganda, prevalence of alcohol use disorder (AUD) is estimated at 9.8% (Kabwama et al., 2016) and some documented consequences to alcohol misuse include the spread of HIV/AIDS (Uganda AIDS Commission, 2007), various somatic and psychiatric disorders, physical disabilities (Affinnih, 2002), …
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Risk management in Australian manufacturing exports : the case of letters of credit to ASEAN
… In the UK, in 2000, losses were estimated to be AUD 305 million (£ 113) through non-compliant documents being presented under Letters of Credit – this amount did not include lost opportunities and cash flow problems. In the same year, a separate USA study of Letter of Credit transactions …
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An investigation of the mental health and psychological resilience of UK armed forces personnel following physical combat-related injury in Afghanistan (Operation Herrick) between 2009 and 2011.
… to assess the prevalence of PTSD, CMD and AUD on admission, in addition to reported levels of Hardiness and Psychological Resilience. Statistical analysis of this data, using Pearson's Chi-Square and Odds Ratio (OR) calculations was conducted to explore relationships between the primary …
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Race-ethnic discrimination, Major Depression, and Alcohol Use Disorder among US-born and immigrant minorities
… Disorder (MDD) and Alcohol Use Disorder (AUD) were examined as outcomes. The dissertation sample (n = 13,914) was drawn from Wave II of the data and included Black, Hispanic, and Asian respondents. The first question addresses the associations between perceived race-ethnic discrimination …
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EFA6/PSD3, Arf6 Modulator, Regulates Ethanol-Induced Behaviors Via the Insulin Receptor Signaling Pathway in Flies and Humans
… understanding of how ethanol use disorders (AUD) develop has been marginal. Our limited progress can be credited to the wide range of effects that ethanol has on the body, absence of a known high affinity receptor to ethanol, and large phenotypic heterogeneities, which have been shown in …
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The effect of childhood trauma in the development of alcohol abuse and alcohol dependence in individuals with social anxiety disorder
… for later development of alcohol use disorders (AUD) and to investigate the association of childhood trauma with the prospective SAD-AUD comorbidity in adults with SAD. Data from fifty seven adult participants (N=57) with a primary diagnosis of SAD (mean age 36.7; 60% male) completed the …
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EFFECTS OF ALCOHOL AND ACAMPROSATE, AN ALCOHOL USE DISORDER TREATMENT, ON NONHUMAN PRIMATE BEHAVIOR AND MEMORY
Alcohol use disorder (AUD) is a major issue facing the population both domestically and abroad. The repeated use of alcohol impairs various behavioral and cognitive functions such as attention and memory and disrupts normal communications between brain regions. These disruptions in communication …
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"We deserve to be seen, heard, and included in recovery spaces:" A content analysis informing the improvement of treatment for alcohol use for sexually diverse individuals
… impacted by alcohol use disorder (AUD) and alcohol-related problems. Though SD individuals utilize alcohol-related treatment services at a higher rate than the general population, the number of SD individuals with AUDs who seek treatment is low compared to the number of SD …
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Treatment coverage, barriers to care and factors associated with help-seeking behaviour of adults with depression and alcohol use disorder in Chitwan district, Nepal
… adults with depression and alcohol use disorder (AUD) in Chitwan district, Nepal before and three years after implementation of the PRIME district mental health care plan (MHCP). Methods: The study was conducted in 10 Village Development Committees of Chitwan district in southern Nepal. The repeat …
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Evaluating Cognitive Changes in Patients Receiving Outpatient Alcohol Treatment
… that individuals within an intensive outpatient AUD program experienced improvements in language and overall cognitive functioning. Additional variables approaching significance include the subtests of story learning, figure copy, semantic fluency, digit span, coding, and the overall attention …
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The impact of alcohol and social context on the startle eyeblink reflex
… pathways of risk for alcohol use disorder (AUD). However, studies that incorporate a social context are still outnumbered by those that examine alcohol’s subjective effects among participants drinking alcohol in isolation. Further, perhaps due to the challenges of capturing automatic …
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Exploring Trends in Disproportionality of Emotional Disturbance Classification After the Individuals with Disabilities Education Improvement Act (IDEIA)
… the nature and the extent of the problem (Aud et al., 2010; Countinho & Oswald, 2002; Skiba et al., 2006, 2008). This study employed a mixed methods multiple case analysis to examine changes in student data trends before and after implementation of the Individuals with Disabilities …
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