Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"ATTR"”.
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Determinants and Monitoring of Response to Disease-Modifying Therapy for Transthyretin Amyloidosis Cardiomyopathy: The ATTR-CM Therapy Study
Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is a heart muscle disease characterized by the accumulation of misfolded transthyretin proteins as amyloid plaques in the myocardial interstitium. In 2020, tafamidis, a medication inhibiting the misfolding of transthyretin, received Health Canada's …
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Bedeutung von Entzündungszellen, Apoptose- und Nekrosemarkern in Myokardbiopsaten mit Amyloidablagerungen und Korrelation klinischer Patienteneigenschaften mit dem AL- und ATTR-Gehalt in Myokardbiopsaten
Die AL- und ATTR-Amyloidose sind die häufigsten Formen der kardialen Amyloidose und gehen häufig mit strukturellen und funktionellen Veränderungen des Herzmuskels sowie einer Herzinsuffizienz einher. Die kardiale Beteiligung ist ein wesentlicher prognostischer Faktor und trägt maßgeblich zur …
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Characterization of the Gifsy-1 Phage Excisionase
… border the integrated phage chromosome, attL and attR. It is believed that the Gifsy-1 phage Int catalyzes a reaction that is chemically identical to that described for the lambda Int protein. This reaction results in chimeric products of the recombination reaction, attL and attR, in which …
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A genetic analysis of bacteriophage lambda integrase-core site interactions
… attB to generate the prophage sites, attL and attR. attP contains the core region, where strand exchange occurs, and the required flanking sequences, the P and P$\sp\prime$ arms. Within the core, there are two Int core-type binding sites. The flanking arm sequences contain binding sites for Int …
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Novel applications of fluorine-18 labelled radiotracers in cardiovascular disease
… were scanned: 18 with cardiac amyloid (10 ATTR and 8 AL), 13 control subjects and 22 patients with aortic stenosis. No differences in myocardial TBR values were observed between participants scanned in Edinburgh and New York. Mean myocardial TBRMEAN values in patients with ATTR amyloid …
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Morphogenese bei Stigmatella aurantiaca : Studien zur Fruchtkörperbildung
… über die ortsspezifische Integration in die attR site komplementiert werden, wenn diese Plasmide ein ca. 1.2 kbp großes Fragment der attB site von S. aurantiaca enthalten.
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Protein/DNA interactions during site-specific recombination
… containing the NBU1 attachment sites attL and attR. The results demonstrate that IntN1 interacts with two core-type sites flanking the region of cleavage and strand exchange on attL and attR as well as six arm-type sites. Two of the arm-type sites are located immediately downstream of the attL …
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Papel da cintilografia com DPD-99mTc na discriminação da amiloidose cardíaca
… de pacientes com amiloidose cardíaca por ATTR, sendo a intensidade das anormalidades observadas maior do que a cintilografia com MDP-99mTc.
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A Critical Edition of the Hexaplaric Fragments of Genesis
… by hexaplaric readings. The third apparatus (Attr) enlists the sources that contain variant attributions from the lemma. The fourth apparatus (Var) helps readers to notice variants or different hexaplaric readings. All of the non-Greek sources (NonGr) cover the hexaplaric materials in Latin, …
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The role of Bacteroides Host Factor A in CTnDOT integration and Holliday junction resolution
… attDOT and attB. For excision, the attL and attR DNA sites are required for the assembly of two separate excisive intasomes before being brought together to reform the circular element. As many as five proteins may participate in excision and four are required. In order to study the …
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A streamlined Workflow for Transposon Mutagenesis in Corynebacterium glutamicum Based on Third-Generation Sequencing and its Application for Advanced Genetic Screens
… Recombination results in the hybrid *attL* and *attR* sites inverting the promoter in between, which renders transcription of the downstream IS*Cg1* active. For this, *bxbI* was integrated into the genome of CR101, resulting in the strain ML102.<br /> Surprisingly, transformation of pML10 into …