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Showing 1 to 1 of 1 for “"ATRX biology"”.
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Exploring the immunologic consequences of ATRX deficiency in glioma
<p>ATRX is a key chromatin regulator that is frequently mutated across multiple cancer types. One of the most common ATRX-mutated tumor types is the adult-type glioma, IDH-mutant, Astrocytoma. It is known that ATRX mutation leads to increases in DNA damage, replication stress, and global epigenetic …