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Showing 1 to 1 of 1 for “"ATM signaling pathway"”.
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Further Insight into the Two Functions of Telomeres: Determining the Role of Tankyrase1 in Telomere Length Regulation and Tin2 in Telomere Protection
… elongation through the removal of TRF1. This pathway appears absent from mouse cells. We demonstrated that murine TRF1, which lacks the tankyrase1-binding motif, is not a substrate for tankyrase1 poly(ADP-ribosyl)sylation in vitro. Furthermore, overexpression of tankyrase1 in mouse nuclei did …