Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"ATGL"”.
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Autophagy and Lipid Homeostasis in C. elegans
… the cytosolic adipose triglyceride lipase-1 (ATGL-1), is required for the reduction in lipid levels observed in autophagy mutants. Depletion of atgl-1 restored the lipid levels in several autophagy mutant backgrounds, such as unc-51/ULK1/2, bec-1/BECN1, atg-7/ATG7 and atg-16.2/ATG16L. …
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The role of skeletal muscle PLIN proteins at rest and following lipolytic stimulation
… and PLIN5) as well as protein interactions with ATGL and HSL at rest and following lipolytic stimulation. In addition, the serine phosphorylation state of PLIN2, PLIN3, and PLIN5 was determined at rest and following lipolytic stimulation. An isolated whole muscle technique was used to study the …
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THE ROLE OF CGI-58/ABHD5 IN LIPID METABOLISM, INFLAMMATION, AND INSULIN ACTION
… an enzyme known as Adipose Triglyceride Lipase (ATGL), which breaks down triglyceride. However, human ATGL mutations do not have the same effect as CGI-58 mutations, suggesting that CGI-58 has an unknown function. The purpose of this dissertation research is to advance the understanding of CGI-58 …
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Regulation of Systemic and Cellular Metabolism In Prostate Cancer By Camkk2 and Elucidation of Atgl’S Role In Disease Progression
… The protein adipose triglyceride lipase (ATGL), the rate-limiting step in the breakdown of triglycerides, was revealed as the top phosphorylated AMPK substrate in metastatic, castration-resistant prostate cancer compared to benign prostate or primary, hormone-naïve prostate cancer patient …
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Endocannabinoid and lipid metabolism genes network analysis in adipose and liver tissue of dairy cows during the transition period
… of genes associated with lipolysis (LIPE, ABDH5, ATGL), fatty acid oxidation (CPT1A, CPT2, ACADVL, ACOX1), oxidative stress (SOD1, SOD2), and genes that are involved in inflammation (TLR9, TLR4, NFE2L2). Expression of CNR2 and NAPEPLD was greater at 7 d in LoBCS due to lower expression at the same …
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Cold-Induced Metabolic Changes in Lean, NAG-1 Transgenic Mice
… higher expression of <em>Glut4 </em>and <em>Atgl</em> in wildtype mice, indicating that NAG-1 does not upregulate expression of thermogenic genes in response to cold exposure. The data from these analyses suggest that NAG-1 does not act synergistically with the b-3 adrenergic stimulated …
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Effect of Morinda citrifolia (Noni)-Enriched Diet on Hepatic Heat Shock Protein and Lipid Metabolism-Related Genes in Heat Stressed Broiler Chickens
… but up-regulated adipose triglyceride lipase (ATGL). Although it did not affect growth performance, Noni supplementation regulated the hepatic expression of lipogenic proteins in a time- and gene-specific manner. Prior to HS, Noni increased ACLY and FASN in acute and chronic experimental …
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Characterization of coconut oil and CLA induced lipolysis
… to decrease adipose triglyceride lipase (ATGL) protein. CO-fed mice had greater fatty acid synthase, stearoyl CoA desaturase 1 mRNA expression and less acetyl CoA carboxylase mRNA expression (P<0.01). Sterol regulatory binding protein 1c and malic enzyme expression was least in CO+CLA-fed …
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Transcriptional adaptation of adipose tissue in dairy cows in response to energy overfeeding
… and early postpartal lipolytic related gene (ATGL and ABHD5) expression in subcutaneous AT, but decreased PDE3B expression during periparturient period. Part of AT from biopsy of -10 and 7 d was used for tissue explant and challenged with hyperphysiological bovine insulin in vitro. …