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Showing 1 to 2 of 2 for “"ATG2"”.

  1. Jak-stat pathway in the control of mycobacterial infections

    … inflammatory signals to regulate expression of Atg2 in Drosophila phagocytes. In isolation or upon infection, STAT activation inhibits Atg2 expression and the ability of other, unknown signals to promote Atg2 expression. Increased Atg2 expression, as is seen in infected animals lacking either …

    kings Repository record for Jak-stat pathway in the control of mycobacterial infections (opens in a new tab)

  2. The role of CASM in the endolysosomal damage response

    … with the bridge-like lipid transfer proteins ATG2A/B following damage in a CASM-dependent manner. This presents a model whereby CASM-dependent ATG8 lipidation following lysosomal damage provides a recruitment platform for effector proteins that could promote resolution of damage via a variety …

    cambridge Repository record for The role of CASM in the endolysosomal damage response (opens in a new tab)