Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"ATG14"”.
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Investigation of mTOR-independent regulation of macroautophagy
… of the key autophagy regulators ATG13, ULK1, ATG14 and TFEB. Consequently, mTORC1 has become a candidate therapeutic target in neurodegeneration and cancer; however, its essential role in other cellular programs has prompted the investigation of mTORC1-independent regulation of autophagy. This …
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Biochemical and Genetic Studies of Beclin 1 Function in Autophagy
… three novel Beclin 1 interaction proteins Atg14L (yeast Atg14-like), Rubicon (RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein) and Nrbf2 were identified from mouse tissues. Gel filtration and co-immunoprecipitation show that these proteins co-exist in one large …