Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"ATG13"”.
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Investigation of mTOR-independent regulation of macroautophagy
… phosphorylation of the key autophagy regulators ATG13, ULK1, ATG14 and TFEB. Consequently, mTORC1 has become a candidate therapeutic target in neurodegeneration and cancer; however, its essential role in other cellular programs has prompted the investigation of mTORC1-independent regulation of …
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Dissecting the Physiological Roles of ULK1/2 in the Mouse Brain
… did not require other autophagy proteins (e.g. ATG13). The defect in ER-to-Golgi trafficking activated the UPR pathway in ULK-deficient cells; both processes were reversed upon expression of SEC16A with a phosphomimetic substitution. Thus, the regulation of ER-to-Golgi trafficking by ULK1/2 is …