Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 116 for “"ASC"”.
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Insights into the mechanisms of translation surveillance using constitutive RNA binding ASC-1 complex mutants
… the pro- teostatic damage caused by truncated nascent polypeptides associated with stalled ribosomes. During RQC, the stalled ribosome is removed from its substrate mRNA through the splitting of its component subunits by the ASC-1 complex (ASCC), enabling the ubiquitylation, extraction and …
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An alternative optimization model and robust experimental design for the Assignment Scheduling Capability for the Unmanned Aerial Vehicles (ASC-U) simulation
… Capability for Unmanned Aerial Vehicles (ASC-U) discrete event simulation to aid in the analysis of future U.S. Army Unmanned Aerial Vehicle (UAV) requirements. TRAC selected ASC-U to provide insight into the programmatic decisions addressed in the U.S. Army UAV-Mix Analysis that directly …
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Histological outcome of atypical squamous cells cannot exclude high-grade squamous intraepithelial lesion (asc-h) papanicolaou smears diagnosed at Groote Schuur hospital
… High grade squamous intraepithelial lesion (ASC-H) category is said to carry a positive predictive value for High grade Squamous Intraepithelial neoplasia (HSIL) that lies between Atypical Squamous Cells of Uncertain Significance (ASC-US) and HSIL. Aim: The aim of this study was to assess the …
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AN AUDIT COMMITTEE MEMBER’S ROLE IN AUDIT ADJUSTMENT DISPUTES: THE EFFECT OF EXTERNAL AUDITOR ATTACHMENT ON AN AUDIT COMMITTEE MEMBER’S ASC 360 ADJUSTMENT DECISIONS.
Audit committee members play a pivotal role in the audit process, specifically, when negotiating disputes between management and the external auditor concerning audit adjustments. According to Auditing Standard 16 (formerly AU Section 380.34-.44), the external auditors are required to discuss, with …
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An investigation of observed Algorithmic Specified Complexity.
… how Algorithmic Specified Complexity (ASC) might serve as a tool, specifically in the area of classification AI, and how well the theory around it predicts the characteristics of random numbers. One evaluated an approach to measuring ASC in pictures by how well it helped in …
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Mobilization of Adipose Stromal Cells In Obesity and Cancer By Sparc and Its Proteolytic Isoforms
… remained unclear. Adipose stromal cells (ASC) are adipose tissue-derived mesenchymal progenitors, abundant in white adipose tissue (WAT). In this study, we show that the ASC pool is expanded in obesity and is associated with promoted tumor growth. Next, by using a chimeric GFP-RFP bone …
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Reaction and Transport Coupling in Multi-Functional Catalysts for Selective Oxidation of Ammonia to Nitrogen
… (popularly known as “Ammonia Slip Catalyst (ASC)” or “AMOx”) comprising Pt/Al2O3 and Cu or Fe-exchanged zeolite is utilized for selective oxidization of NH3 to N2 in the diesel engine emission control system. Pt catalyzes the oxidation of NH3 to four products (N2, N2O, NO, NO2) while the …
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High fidelity hydrographic surveys using and autonomous surface craft
… techniques. Since 1993 Autonomous Surface Craft (ASC) have been under development at the MIT Sea Grant College Program. Hydrographic surveying was the first practical mission approached by an ASC. The ASC ARTEMIS used simple navigation and control systems and a basic recreational depth sounder to …
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Adipose stromal cells enhance keratinocyte survival and migration in vitro, and graft revascularization in mouse wound healing model
… retention due to infection, hematoma, and low vascularity at the recipient site are other drawbacks associated with the use of skin grafts as a primary treatment for severe burn wounds. As such, research has been done into alternative treatments, which include but are not limited to artificial …
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Self-renewal pattern-associated genes and their role in adult stem cell functions
Molecular markers for adult stem cells (ASCs) are highly demanded for research and clinical applications. The development of specific molecular markers for ASCs has been difficult mainly due to the technical barriers in the identification and isolation of rare ASCs. Previously, reported …
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An Analysis of Functional Differences in Implicit Learning
… differences between Autism Spectrum Condition (ASC) and Typically Developing (TD) individuals (e.g., L. G. Klinger, Klinger, & Pohlig, 2007). Overall, the results from the four studies presented in this thesis emphasised a lack of functional differences in implicit learning between individuals. …
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Visualisation of innate immune signalling complexes in cells by cryo-electron tomography
… induces oligomerisation of adaptor protein ASC into large puncta. Caspase-1 is recruited and then cleaved to initiate caspase-1 dependent pyroptosis and the release of pro-inflammatory cytokines. Previous structural studies have shown mechanistic models of the signalling components involved. …
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Development of an antigen-specific ELISPOT to detect intestinal antibody responses to the swine whipworm, Trichuris suis
… IgG and IgA antibody secreting cells (ASC) from gut-associated lymphoid tissues (GALT) [mesenteric lymph node explants from jejunal region of small intestine (SI-MLN) and cecum in large intestine (C-MLN); and ileocecal Peyer's patches (IC-PP)] and lamina propria from the proximal colon …
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Anti-Obesity Effects of Adipose-Targeting Resveratrol Nanocarriers
… via inducing adipose stromal stem cells (ASC) differentiation into beige adipocytes in WAT. But its low levels of aqueous solubility, bioavailability, and targeting specificity limit its application in obesity. We have successfully synthesized biocompatible and biodegradable R encapsulated …
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Investigating communicative dissonance within relationships of adults with Asperger’s Syndrome (ASD Level 1)
The key features of Autism Spectrum Conditions (ASC) include marked and lifelong impairments in social interaction. Social interaction is a fundamental component of relationships. Despite the momentum of worldwide research on ASC, there is insufficient empirical study on adults with ASC and their …
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Investigating the Contribution of the Inflammasome to Persistent Pain States
… speck-like protein containing a CARD (ASC), and pro-caspase-1. It is known to assemble in response to a variety of exogenous and endogenous danger signals (eg adenosine-5’-triphosphate (ATP), monosodium urate (MSU) crystals).<br/>Data presented in this thesis demonstrates that, …
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Characterization and application of adipose derived stem cells following burn injury
… signaling in adipose-derived stem cells (ASCs), which hold potential for healing burn wounds or generating skin substitutes. Using a 60% rat scald burn model, we investigated the cellular source of inflammation within adipose tissue and whether inflammation affects ASC fate and function. …
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Functional Tissue Engineering of Cartilage Using Adipose-derived Stem Cells
… a mechanical function. Because cartilage is avascular and aneural, it has little capacity for self-repair if damaged. One repair strategy is through a functional tissue engineering approach using adipose-derived stem cells (ASCs). ASCs are an abundant progenitor cell source easily obtained …
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Extending the reach of drilling: better wellbore trajectory and torque & drag models
… trajectory model, the Advanced Spline-Curves [ASC] borehole trajectory model, has been developed to overcome these limitations. The principal method proposed using the spline-curves does not make the potentially unrealistic assumption of a constant curvature arc between survey measurements. It …
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Investigating Adult Stem Cell Lineage Specification in the Freshwater Flatworm Schmidtea mediterranea
Adult stem cells (ASCs) serve to facilitate tissue turnover during the lifespan of an organism. The goal of my research has been to deepen our understanding of how ASCs become specified towards differentiation to produce physiologically functional cell types. To this end, I have chosen to use the …
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