Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"ASBT"”.
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Charakterisierung des Gallensäuretransporters ASBT am Oozyten-Expressionssystem
… investigations on the bile acid transporter ASBT (apical bile acid transporter) have been conducted. This transporter physiologically occurs in the apical cell membrane of cholangiocytes, ileocytes and cells of the proximal tube of the kidney. It is among other essential for the re uptake of …
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Regulation des renalen Natrium-abhängigen Gallensäuren-Transporters (ASBT) durch Sexualhormone und Glukokortikoide
… by the sodium-dependent bile acid transporter (ASBT) localized in the apical brush border membrane of the proximal tubular cell. The aim of the present study was to assess whether the ASBT-mediated transport of the bile acid taurocholate is regulated by sex hormones or glucocorticoids. In-vitro …
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Taurocholat-Transport in isolierten proximalen Tubuluszellen der Ratte : Einfluss einer extrahepatischen Cholestase
… apical sodium-dependent bile salt transporter (asbt). Hence, with normal conditions, urinary excretion of bile acids is negligible low. During extrahepatic cholestasis, when bile acid concentrations in the plasma are enhanced, there is, according to our studies, an adaptive renal mechanism …
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The Role of OSTα-OSTβ and Bile Acid Transport in Intestinal Disorders Aand Metabolic Disease
… is facilitated by special transporters, the ASBT and OST-OST. Inherited or acquired defects in hepatic bile acid export, termed cholestasis, results in bile acid accumulation in hepatocytes and is a well-described form of liver injury and disease. In contrast to liver, it was unknown whether …
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The Metabolic Impact of the Gut-Liver Bile Acid Signaling in Metabolic and Inflammatory Liver Disease
… apical sodium-dependent bile salt transporter (ASBT) inhibitor-treated mice as experimental models and studied the effects on metabolic pathways in the liver and the underlying mechanisms. The effect of blocking intestinal bile acid uptake on hepatic metabolic pathways and the underlying …
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Sédentarité des personnes aînées : seuils critiques et impacts métaboliques
… sédentaire absolu (absolute sedentary time; ASBT). En revanche, la même comparaison effectuée avec le temps sédentaire relatif (relative sedentary time; RSBT) montre que le groupe RSBT‑Q4 (n = 660), comparé au groupe RSBT‑Q1 (n = 660), présente une prévalence significativement plus élevée …
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Bile Acid Induced Diarrhoea Pathophysiological and Clinical Aspects
A common cause for referral to gastroenterologists is chronic watery diarrhoea. Approximately 40% of these patients have idiopathic bile acid malabsorption (BAM) – a condition with unknown aetiology. The 75SeHCAT test, which correlates inversely with faecal excretion and hepatic synthesis of bile …