Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 63 for “"ARGs"”.
-
Developing a Computational Pipeline for Detecting Multi-Functional Antibiotic Resistance Genes in Metagenomics Data
… in the spread of antibiotic resistance genes (ARGs), which confer antibiotic resistance to bacteria. Detecting ARGs in the environment is the first step in monitoring and controlling antibiotic resistance. In recent years, next-generation sequencing of environmental samples (metagenomic …
-
DeepARG+ - A Computational Pipeline for the Prediction of Antibiotic Resistance
… of emerging antibiotic resistance genes (ARGs) from such data, but there are a limited number of pipelines that enable the identification of novel ARGs belonging to diverse antibiotic classes at present. Therefore, there is a need for the development of computational pipelines that can …
-
Metagenomic Data Analysis Using Extremely Randomized Tree Algorithm
Many antibiotic resistance genes (ARGs) conferring resistance to a broad range of antibiotics have often been detected in aquatic environments such as untreated and treated wastewater, river and surface water. ARG proliferation in the aquatic environment could depend upon various factors such as …
-
Antimicrobial resistance gene monitoring in aquatic environments
… data quickly and easily for the presence of ARGs is crucial in order to facilitate their monitoring in the environment. As current laboratory methods for the detection and surveillance of antimicrobial resistant bacteria in the environment were limited in their effectiveness and scope, the …
-
Effect of Soil Type, Composting, and Antibiotic Use on Fate of Antibiotic Resistance Genes and Microbial Community Composition in Dairy and Beef Manure Applied Soils
… the spread of antibiotic resistance genes (ARGs) from farm to fork. A microcosm-scale study evaluated the effect of prior antibiotic use (manure-based soil amendments generated from dairy and beef cattle with or without antibiotic administration), composting, and soil type on the quantity of …
-
Recovery of Antibiotic Resistance Genes From Agricultural Runoff
… as reservoirs of antibiotic resistance genes (ARGs) and antibiotic resistant bacteria, which can pass resistance on in the livestock's manure. It is important to understand the fate of antibiotic resistance genes and resistant bacteria in the environment after land-application of manure-based …
-
Airborne Dissemination of Antibiotic Resistance Genes Near Farms and Effectiveness of Ionization Against Airborne Bacteria in a Classroom
… dissemination of antibiotic resistance genes (ARGs) in the atmosphere to an extent that is not yet well understood. Chapters 2 and 3 of this dissertation characterize ARGs in the atmosphere through a literature review and experimental observations at two agricultural sites, respectively. A …
-
Fate of Antibiotic Resistance Genes During Anaerobic Digestion of Wastewater Solids
… bacteria (ARBs), antibiotic resistance genes (ARGs), and the environment through discharge of treated effluent and land application of biosolids. Recent studies observing an apparent resuscitation of pathogens and pathogen indicators and the widening realization of the importance of addressing …
-
Shotgun metagenomic analysis of antimicrobial resistance in wastewater
… bacteria (ARB), and antibiotic resistance genes (ARGs) disposed of or excreted by human populations. Hospital waste water is of special interest as a potential focused monitoring point and in general research is needed to establish the benefits of both on-site and community-scale wastewater …
-
Effect of wastewater colloids on membrane removal of microconstituent antibiotic resistance genes
… generated antibiotic resistance genes (ARGs) are considered emerging contaminants, as they are associated with a critical human health challenge, are persist independent of a bacterial host, are subject to transfer between bacteria, and are present at amplified levels in human-impacted …
-
Impact of Wastewater Effluent on Surface Water Resistomes in a Small Lower-Income Community with Deteriorated Sewage Infrastructure
… bacteria and antibiotic resistance genes (ARGs). Consequently, this has led to a global antimicrobial resistance (AMR) crisis associated with an estimated 4.71 million deaths globally in 2021. Due to inputs of antimicrobials and antibiotics excreted and flushed down the drain, nutrient rich …
-
Occurrence and Control of Microbial Contaminants of Emerging Concern through the Urban Water Cycle: Molecular Profiling of Opportunistic Pathogens and Antibiotic Resistance
… knowledge about the occurrence of OPs and ARGs across these water systems and highlights trends that may be of value in developing management strategies for limiting their regrowth and transmission. Field studies of two surface water catchments impacted by stormwater runoff demonstrated the …
-
Integrative Metagenomic Approaches to Study Antibiotic Resistance Genes and Microbial Functions in the Preterm Infant Gut Microbiome
… and persistence of antibiotic resistance genes (ARGs). As microbial colonization during this period shapes the resistome, understanding the factors driving ARG distribution and persistence are essential. This thesis investigated the distribution and genomic context of ARGs in the gut microbiome …
-
Antibiotic Resistance Genes in Marquette County Michigan's Wastewater
… survive and pass antibiotic resistance genes (ARGs) to their progeny cells. Few ARG studies have utilized wastewater influent samples as a method of surveillance in rural communities in the United States. This study investigated ARGs in Michigan’s Upper Peninsula. Two samples were collected …
-
Fate and Impacts of Contaminants of Emerging Concern during Wastewater Treatment
… the fate of antibiotic resistance genes (ARGs) and engineered nanomaterials (ENMs) as representative contaminants of emerging concern in wastewater treatment plants (WWTPs). WWTPs may have their performance impacted by ENMs and may also serve as a reservoir and point of release for both …
-
Improved monitoring of emerging environmental biocontaminants through (nano)biosensors and molecular analyses
… and/or sharing of antibiotic resistance genes (ARGs) among bacteria via horizontal gene transfer, with carriage of ARGs by pathogenic bacteria of particular concern to human health. While most attention to stopping the spread of antibiotic resistance has been devoted to the clinic, it is …
-
Aggrecan fragments as biomarkers in osteoarthritis
… disease activity. Quantification by ELISA of SF ARGS showed that SF ARGS better distinguished samples from patients with knee joint disease from samples obtained from knee healthy individuals than aggrecan measures not specific for this neoepitope. In patients meniscectomized 18 years earlier, SF …
-
Assessing Vulnerabilities to the Spread of Pathogens and Antibiotic Resistance in Agricultural and Water Systems Using Culture-, Molecular-, and Metagenomic-based Techniques
… bacteria (ARB) and antibiotic resistance genes (ARGs). Key systems that were the focus of this effort included nutrient reuse (wastewater-derived biosolids and cattle-derived manure), water reuse, and drinking water systems disrupted by a major hurricane. A field study was carried out to survey a …
-
Advancing Monitoring and Mitigation of Antibiotic Resistance in Wastewater Treatment Plants and Water Reuse Systems
… resistant bacteria, antibiotic resistance genes (ARGs), and pathogens, thus serving as key point of interest for the surveillance of antibiotic resistance (AR) dissemination. This thesis advances knowledge about the fate of AR indicators throughout treatment and reuse. The field study informs …
-
Detection of antibiotic resistance genes in gardening composts
… standard curves. 95 antibiotic resistance genes (ARGs) were relatively quantified by comparing the abundance of the target gene with the abundance of the 16S rRNA gene. The relative abundance of target genes in each compost sample was then compared with that in control soil to get the enrichment …
Page 1 of 4