Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"ARE-mRNA"”.
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Ribonomic Control During Global Brain Ischemia And Reperfusion
… global brain ischemia. The main findings are summarized:</p> <p>1. The main form of ELAV protein family member detected in CA1/CA3 in Hu protein immunoprecipitation and polysomes was HuB (Rel-N1). HuB is present in control CA3, 8 hr reperfused CA3, and 8 hr reperfused CA1, but absent from …
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The role of phospholipids in the growth and development of Streptomyces
… process has not been investigated. Six genes are thought to be responsible for phospholipid biosynthesis in S. coelicolor, SCO1389, SCO1527, SCO5628, SCO5753, SCO6467 and SCO6468. SCO1389 is predicted to encode a cardiolipin synthase that is an essential gene in this organism. When this gene …
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THE ROLE OF THE RNA-BINDING PROTEIN TRISTETRAPROLIN IN CERVICAL AND COLORECTAL CANCERS
… and cancer-associated genes. These transcripts are targeted for rapid degradation through AU-rich element (ARE) motifs present in the mRNA 3' untranslated region (3'UTR). Tristetraprolin (TTP) is an RNA-binding protein that plays a significant role in regulating the expression of ARE-containing …
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Regulation of cellular growth and identification of stromal gene signatures in breast cancer
… of cells. In cancer, these regulated processes are disrupted, resulting in uncontrolled cell growth. Regulation of RNA stability and turnover is important to maintain cellular homeostasis and can be controlled by various mechanisms. During stress, the cell can form cytoplasmic complexes of …
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The Regulation of ARE-Mediated mRNA Decay During Colorectal Tumorigenesis
… regulated by cis-acting AU-rich elements (ARE) present in the 3' untranslated region (3'UTR) of their mRNA, thereby targeting them for rapid decay in a process known as ARE-mediated mRNA decay. It has been previously shown that ARE-mediated mRNA decay occurs in cytoplasmic RNA decay centers …