Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 2 of 2 for “"APP secretion"”.
-
Cellular Trafficking and Processing Pathways of the Alzheimer β/A4 Amyloid Precursor Protein
… the integral membrane amyloid precursor protein (APP). Secreted truncated forms of APP found in blood plasma and cerebrospinal fluid arise by proteolytic cleavage of APP within the β/A4 amyloid domain, precluding the possibility of amyloidogenesis for that population of molecules. The routes of …
-
Processing of Alzheimer's amyloid precursor protein in cultured cells.
… (betaA4), from amyloid precursor protein (APP), is a key pathology in Alzheimer's disease (AD). The single APP gene is spliced to give 3 major isoforms. In the majority of body tissues, the most common APP isoforms are APP[751] and APP[770], which both contain a Kunitz protease inhibitor …