Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"APOA1"”.
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Effects of APOA1/C3/A4/A5 Gene Cluster and Flavonoids Intake on Cardiovascular Disease Risk Factors in U.S. Populations
… consumption of flavonoids, the prevalence of <em>APOA1/C3/A4/A5</em> gene cluster, the interaction between these genes and flavonoids intake on how they impact cardiovascular disease (CVD) risks among U.S. adults. We focused on four aims: (1) to estimate the dietary flavonoids intake among U.S. …
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Identification and Characterization of Genes Associated with <i>V-Jun</i> Induced Cell Transformation
… identity to the chicken Apolipoprotein A1 (ApoA1) gene. Northern blot analysis demonstrates that the steady state levels of ApoA1 mRNA in RCAS is 3 to 10 times higher than in VJ-1 cells, indicating that v-Jun might repress this gene by transcriptional mechanisms. To investigate this …
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The cholesterol efflux protein ABCA1 skews macrophages towards an anti-tumor phenotype and consequently impacts cancer progression
… cholesterol from macrophages to a lipid-poor ApoA1 protein and facilitates the formation of nascent HDL via the reverse cholesterol transport pathway. We leveraged this mechanism to therapeutically target ABCA1 using ApoA1 mimetics 5A and 4F. Our data so far indicates that ApoA1 mimetics …
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Study of anti-inflammatory functions of HDL in experimental mouse models
… were compared to Apolipoprotein A-I-deficient (Apoa1-/-) mice, which lack classical HDL and are known to have an increased response to LPS, and control wild-type (WT) mice. Characterization of apolipoprotein composition of HDL, revealed that LCAT-deficient HDL is primarily composed of ApoE, …
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Effects of close-up dietary energy strategy and prepartal dietary monensin on hepatic mRNA expression of enzymes involved in glucose and lipid metabolism in transition cows
… (CPT1A, ACOX1, ATP5G1), lipid metabolism genes (APOA1, APOB, FADS2, SCD, HMGCR), inflammation, acute phase response, and detoxification/oxidative stress genes (TNF, IL6, HP, GSTM1), growth hormone/IGF-1 axis genes (GHR, IGF1) and transcription factors (FOXA2, HNF4A, NR4A1, SREBPF2). In cows fed …
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THE OMEGA-6: OMEGA-3 FATTY ACID RATIO IN SWINE NUTRITION: LONG-TERM EFFECTS ON PERFORMANCE, MILK FATTY ACID PROFILES, OXIDATIVE STATUS, AND PROTEOMES
… and a decrease in negative APPs, i.e., APOA1, while by the end of lactation, this APR has dissipated and APOA1, APOA2, and APOC3 were all increased. Piglet serum proteomics: Maternal LR diet enhanced piglet host protective response via regulating the expression of C3, SAA, SERPINA3, …
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The Effect Of Proalgazyme And Its Subfractions On Lipid Metabolism In Diet Induced Hypercholesterolemic Hamsters: Correlation With Plasma Metabolomic Profile
… cholesterol transport metabolism, ie, ApoA1, ABCA1, CETP, and SRB1. Lipid profile was correlated with plasma metabolomic profile using 1D 1H NMR spectroscopy and the biologically active fraction has been identified. </p> <p>Further, the study aimed to determine the therapeutic effect of …
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IMPORTANCE OF SUPPLYING DAIRY COWS WITH ESSENTIAL FATTY ACIDS (EFA) AND CONJUGATED LINOLEIC ACIDS (CLA) DURING THE TRANSITION PERIOD ON METABOLISM AND HEALTH
… of apolipoproteins (APO) containing APOC3, APOA1, APOA4, and APOC4 was increased in response to EFA+CLA according to the stage of lactation. Overabundant APO were annotated by GO (gene ontology) terms related to triglyceride (TAG) homeostasis, cholesterol and lipoprotein metabolisms, …
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Understanding the relationship between high-density lipoprotein (HDL) subclass distribution and functionality in patients at risk of cardiovascular disease
… measurements included apolipoproteins A1 and M (ApoA1 and ApoM), paraoxonase (PON1) and platelet activating factor acetylhydrolase (PAF-AH) expression (using Western blotting) and sphingosine-1-phosphate (S1P) content (using mass spectometry). Levels of large, intermediate and small HDL …
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Development of a multi-stage purification process for serum-derived exosomes and evaluation of their regenerative capacity
… the multi-step purification (UC DG SEC) ApoB and ApoA1 were not detectable by enzyme-linked immunosorbent assay and western blotting respectively. The UC DG SEC isolates were positive for CD9 and TSG101 and morphologically, as viewed by transmission electron microscopy, had the canonical exosome …
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Effects of dietary fat saturation on lipoprotein metabolism in rodents and humans
… genes. No significant differences in ABCA1, ApoA1, CETP or SR-B1 were observed between the diet groups compared with Hi-LM diet. The data suggested no additional adverse effects on CHD risk factors compared with Hi-LM diet.</p> <p> Carbohydrates are generally considered a safe replacement for …
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Identifying circulating biomarkers in a cohort of hypercholesterolaemic patients with statin intolerance from Gauteng, South Africa
… Despite the lack of a significant difference in ApoA1 levels between the control, statin users, and statin-naïve groups, the inverse correlation between miR-33a expression and ApoA1 levels observed in the study supports the notion that miR-33a has a regulatory influence on cholesterol metabolism. …
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Gene and Protein Profiling of the Preeclamptic Placenta
Aims State-of-the-art methodology was used to screen and profile the placenta, gene and protein expression, for changes related to preeclampsia (PE) and cases with increased resistance in the uterine arteries. Women with increased resistance in the uterine arteries have increased risk of developing …