Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"ANTICOAGULATION THERAPY"”.
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Early Identification and Intervention in Patients with Atrial Fibrillation Using an Implantable Cardiac Monitor to Significantly Improve Guideline-Based Anticoagulation Therapy in an Outpatient Cardiology Clinic
… for stroke should receive OAC; however, this therapy is prescribed in less than 55% of eligible patients. AF accounts for nearly 1 in 7 strokes and affects approximately 5.8 million people in the United States.</p> <p>Objectives: The purpose of this study is to identify and intervene in …
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Shared Decision-Making to Improve Uptake of and Adherence with Oral Anticoagulation Therapy for Stroke Prevention in Patients with Atrial Fibrillation: Initial Clinical Evaluation of a Web-Based Patient Decision Aid
… long-term adherence to oral anticoagulant (OAC) therapy. Despite the established benefits of OACs in reducing stroke risk, many patients do not initiate therapy or discontinue it prematurely. This multi-method doctoral thesis aimed to examine the issue of OAC non-persistence and to explore the …
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Increasing Inclusion of Participants, Leveraging Gut Microbiomes, and Optimizing Machine Learning Models to Advance Warfarin Precision Medicine
… of precision medicine through rigorous research. Anticoagulation therapy with the popular vitamin K antagonist, warfarin, can be challenging due to large interpatient dose variability and a narrow therapeutic window. Warfarin genotype-guided dose prediction models currently can account for …
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Seeding of Titanium Surfaces and Nitinol Stents with Blood-Derived Endothelial Cells
… complications and also reduce the need for risky anticoagulation therapy following implantation of such devices. We developed a novel cell therapy for seeding autologous endothelium onto blood-contacting vascular stents at the point of care to reduce thrombosis and stent restenosis. The proposed …
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International Normalised Ratio Monitoring in Children: Comparing the accuracy of portable point-of-care monitors to standard of care laboratory monitoring at Red Cross War Memorial Children's Hospital
… an increasing trend in the use of long-term oral anticoagulation therapy in children. Monitoring the international normalised ratio (INR) is an integral part in management of these patients, but standard laboratory testing of the INR presents challenges in this age group. Point-of-care INR …
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Novel Sulfated 4-Hydroxycinnamic Acid Oligomers as Potent Anticoagulants
… conditions creates a huge need for anticoagulation therapy. Thrombin and factor Xa have been prime targets for regulation of clotting through the direct and indirect mechanism of inhibition. This work investigates chemo-enzymatically prepared oligomers of 4-hydroxycinnamic acids …
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Die Mikrodiagonalpumpe : tierexperimentelle Untersuchung eines Linksherzunterstützungssystems unter besonderer Berücksichtigung des Thromboembolie-Risikos
… bridge time to transplantation or as live saving therapy. Over the last years a couple of pulsatile and non-pulsatile assist devices have been developed, aiming to improve the current situation. Despite the continuous enhancement of these assist devices they still are affiliated with a …
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MOLECULAR MODELING STUDIES OF HEPARIN AND HEPARIN MIMETICS BINDING TO COAGULATION PROTEINS
… of heparin with antithrombin is the basis for anticoagulation therapy. Heparin accelerates the antithrombin mediated inhibition of factor Xa and thrombin by a conformational activation mechansism and bridging mechanism, respectively. The sequence specific pentasaccharide DEFGH in full length …
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Aportaciones a un modelo de inserción de servicios asistenciales basados en telemedicina para su uso y validación en el seguimiento de pacientes crónicos
… platform, in the arterial hypertension and oral anticoagulation therapy settings.