Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"AMPAR function"”.
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Studies of nicotinic acetylcholine receptors containing α4 and α6 subunits in nicotine-induced synaptic plasticity in brain reward areas
… including the enhancement of AMPA receptor (AMPAR) function. This enhancement sensitizes the VTA to excitatory input and promotes drug seeking in animal models. However, which nAChR subtype(s) are responsible for initiating these cellular changes is poorly understood. nAChRs containing the α6 …
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Regulation of AMPA receptor acetylation and translation by SIRT2 and AMPK: the molecular mechanisms and implications in memory formation
… acid receptors (AMPARs) are ligand-gated glutamatergic ion channels that mediate most excitatory neurotransmission in the brain. Alterations in AMPAR synaptic accumulation mediate synaptic plasticity, including long-term potentiation, long-term depression and …
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Identification and functional characterisation of synaptic AMPA receptor-interacting proteins
… primarily by AMPA-type glutamate receptors (AMPARs), and is crucial for the transfer and storage of information in the brain. The AMPAR engages in numerous protein interactions, modulating receptor trafficking, channel gating, synaptic positioning, and ultimately synaptic strength. iGluR …
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Role of the different domains of PSD-95 in basal synaptic transmission
Die Fähigkeit des Gehirns, zu lernen und somit Information im Gedächtnis einzuspeichern, korreliert mit Veränderungen in der Stärke der synaptischen Transmission. An exzitatorischen Synapsen in der CA1-Region des Hippocampus wird die synaptische Transmission imWesentlichen durch in der …