Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"AM630"”.
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The human cannabinoid CB(1) receptor stably expressed in Chinese hamster ovary cells provides a model system to predict the pharmacological effects of cannabinoids in man
… is a competitive antagonist and SR141716A and AM630 are inverse agonists. The results for the full and partial agonists are consistent with those reported for these: compounds in mammalian brain. The findings that Δ⁹-THC is a competitive antagonist and that SR141716A and AM630 are inverse …
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Pain-modulating effects of peripheral (CB2) cannabinoid receptors
… by the CB2 receptor-selective antagonist, AM630, and was not observed in skin from CB2 receptor knockout mice, demonstrating that it is mediated by CB2 receptor. These results suggest that CB2 receptor activation produces antinociception by stimulating the release of beta-endorphin from …
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CANNABINOID RECEPTORS (CB) IN COCHLEA: CHARACTERIZATION AND OTOPROTECTIVE FUNCTIONS
… TNF- α. We also found that blocking of CB2 by AM630 itself resulted in hearing loss and loss in CB2 receptors, indicating eCB system is tonically active and could be important for physiological function of the cochlea. Indeed, we observed that inhibition of DAGL- α by RHC80267 results in HL. …
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The effect of synthetic cannabinoids on wound healing of chondrocytes monolayers and pseudo 3D cartilage tissue. Effect of different concentrations of synthetic cannabinoids WIN55, 212-2, URB602 and HU-308 with and without their antagonists on wound healing of chondrocyte monolayers and pseudo 3D cartilage tissue.
Studies have been conducted to highlight the anti-inflammatory and immunosuppressive properties of cannabinoids and also their potentials for cartilage repair and regeneration. Various wound healing techniques can be used to investigate the mechanisms of chondrocyte repair in monolayers or three …