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Showing 1 to 2 of 2 for “"ALI-CO"”.

  1. Elucidating Astrocytic Diversity in Human Cerebral Organoids

    … may inform therapeutic targets. The lack of consensus regarding astrocyte diversity is in part due to the difficulty of modelling the human brain and astrocyte specification in a dish and the significant differences found between mouse and human astrocytes. To overcome these difficulties, …

    cambridge Repository record for Elucidating Astrocytic Diversity in Human Cerebral Organoids (opens in a new tab)

  2. Investigating the role of ZEB2 in the establishment of neuroepithelial architecture and axon tract formation

    A bioinformatic screen of comparative genomic and transcriptomic datasets identified the transcription factor ZEB2 as a putative regulator of brain size. In this work we show that in both human brain organoids and mouse embryos ZEB2 is expressed in telencephalic neuroepithelial cells (NECs) before …

    cambridge Repository record for Investigating the role of ZEB2 in the establishment of neuroepithelial architecture and axon tract formation (opens in a new tab)