Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"ALDH1"”.
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Impact of Dietary Bioactive Components in Chronic Diseases Using Nutrigenomics, Nutriepigenomics, and Metagenomics Approaches
… stem cell (CSC) marker aldehyde dehydrogenase 1 (ALDH1) with concomitant induction of oxidative stress and apoptosis in cervical CSCs, conferring improved therapeutic outcomes in cancer patients. This dissertation presents a body of translational research work on diet-gene interaction, which is …
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The Role of Tumor Suppressor Dear1 In The Acquisition of Mammary Stem/Progenitor Cell Properties
… cell marker aldehyde dehydrogenase (ALDH1) and display a basal-like phenotype through repression of CD24 and EpCAM expression. There is significant upregulation of master EMT and stem cell regulators, including SNAI2, in <em>DEAR1</em>-KD HMECs and I show that DEAR1 binds to and …
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Role of Mir-19A Released By Inflammatory Breast Cancer Cells In The Regulation of Dendritic Cell Functions: In Vitro Model of Crosstalk In The Tumor Microenvironment of Inflammatory Breast Cancer
… the induction of CD44<sup>+</sup>CD24<sup>-</sup>ALDH1<sup>+</sup> cancer stem cells (CSCs) with epithelial-to-mesenchymal transition (EMT) characteristics.</p> <p>In conclusion, in IBC tumor microenvironment IL-6/miR-19a axis can represent a self-sustaining loop able to maintain a …
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Molecular Analysis of Breast Cancer Transcriptomes, Genomes, and Circulating Tumor DNA
… was associated with expression of the CSC marker ALDH1 and the CSC phenotype CD44+/CD24- was correlated to alternatively spliced isoforms in tumors. The isoforms were differentially expressed in molecular subtypes and HER2 and EGFR positive tumors were associated to CD44S and CD44v8-10, …
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Bone morphogenetic protein (BMP-7) και μοριακά δίκτυα δυνητικών stem κυττάρων στον νεφρό
… δείκτη stem κυττάρων την αλδεϋδική δεϋδρογενάση ALDH1, η οποία σχετίζεται με τον καθοριστικό για την τύχη των stem κυττάρων παράγοντα ρετινοϊκό οξύ. Τα ιστικά δείγματα προήλθαν από 49 ασθενείς (30 άνδρες,19 γυναίκες), ηλικίας από 50 έως 79 ετών. Η ανοσοϊστοχημική μέθοδος εφαρμόσθηκε σε …