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Showing 1 to 4 of 4 for “"AGS3"”.
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No-Independent Modulation of Soluble Guanylyl Cyclase (Sgc) Activity and Function
… protein, activator of G-protein signaling 3 (AGS3), attenuates the response of sGC to activators in cell lysates.</p> <p>In this report, we provide evidence that sGC activity and responsiveness are increased in AGS3-deficient mice. We found that AGS3-deficient mice not only have a lower …
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Regulation of Guanine Nucelotide Exchange in Inhibitory G Protein Alpha Subunit by Activator of G Protein Signaling 3 and Novel Regulatory Peptides
… are GDIs. Activator of G protein signaling 3 (AGS3), a GDI containing four GoLoco motifs in its C-terminal domain (AGS3-C), binds specifically to GDP-bound Gai1 and inhibits the binding of GTP to Gai1. The stoichiometry and dissociation constant for the binding of AGS3-C to Gai1, determined …
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Novel Modulation of Adenylyl Cyclase Type 2
… signaling. Activator of G protein signaling 3 (AGS3) is a G protein modulator that binds Gαi subunits in the GDP-bound state, implicating AGS3 as an important regulatorof Gi-coupled receptor signaling. We studied the ability of AGS3 to modulate recombinant adenylyl cyclase(AC) type 1 and 2 …
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Effects of Quorum Quenchers on Aspergillus fumigatus Conidia Aggregation, Adhesion to Surfaces, and Biofilm Formation
… change from hydrophobic to hydrophilic property. ags3 down-regulation approved with real-time PCR assay showed triclosan’s quorum sensing inhibitory role against A. fumigatus. This was through inhibiting conidia aggregation, and hence prohibiting initiation of quorum sensing signalling pathway. …