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Showing 1 to 20 of 619 for “"AERUGINOSA"”.
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Regulating rsmA Expression in Pseudomonas aeruginosa
<p><em>Pseudomonas aeruginosa</em>, a Gram-negative bacillus, commonly infects immunocompromised individuals and uses a variety of virulence factors to persist in these hosts. The posttranscriptional regulator, RsmA, plays a role in the expression of many virulence factors in <em>P. …
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Effect of Exopolysaccharides on Pseudomonas aeruginosa Physiology
… biofilm matrix of the opportunistic pathogen P. aeruginosa contains up to three chemically distinct EPS: Pel, Psl, and alginate. EPS production is necessary for robust P. aeruginosa biofilms formation, however, the amount and number of EPS produced varies between strains and growth conditions. …
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Structure and dynamics of Pseudomonas aeruginosa ICP
Pseudomonas aeruginosa inhibitor of cysteine peptidases (PA-ICP) is a potent protein inhibitor of papain-like cysteine peptidases (CPs) identified in Pseudomonas aeruginosa, an opportunistic pathogenic bacteria that can cause severe infections in human. It belongs to the newly characterized natural …
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Studies on survival of Pseudomonas aeruginosa 6750
The growth of Pseudomonas aeruginosa 6750 as a biofilm was investigated using a novel system based on that of Gilbert et al (1989). The aim was to test the effect of controlled growth of the organism on antibiotic susceptibility and examine the survival of the organism as a biofilm. During the …
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Distribution of the Cytotoxin Gene in Pseudomonas Aeruginosa
<p><em>Pseudomonas aeruginosa</em> is an opportunistic Gram negative facultative anaerobe. It is found primarily in the soil, but is ubiquitous in nature. The clinical significance of the organism is attributed to its innate resistance to antibiotics and its ability to survive in the presence of …
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Analysis of the hex regulon in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen whose defense mechanisms include biofilm production through carbohydrate metabolism. The activity of the enzymes in the hex regulon are required for catabolism of glucose and these activities are coordinately regulated. Previous work has shown …
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Functions of alternative ClpP subunits in Pseudomonas aeruginosa
… The opportunistic pathogen Pseudomonas aeruginosa is unusual in that it contains two isoforms of the subunits that form the ClpP peptidase chamber. These isoforms, PaClpP1 and PaClpP2, have not been well characterized previously and their specific functions are largely elusive. This work …
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EXPLORING THE MECHANISM OF ALGINATE ACETYLATION IN PSEUDOMONAS AERUGINOSA
The opportunistic pathogen P. aeruginosa is the leading cause of morbidity and mortality in cystic fibrosis patients. During chronic infection of the cystic fibrosis lung, P. aeruginosa undergoes conversion to a mucoid phenotype, constitutively producing the exopolysaccharide alginate, composed of …
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Implications of Microcystin Production in Microcystis aeruginosa PCC 7806
… common bloom-forming cyanobacterium Microcystis aeruginosa. In a first attempt, the effect of elevated light intensity on microcystin production and its binding to cellular proteins was studied. Therefore, conventional microcystin quantification techniques were combined with protein-biochemical …
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Evolution of Pseudomonas aeruginosa in the Cystic Fibrosis Lung
<p>ABSTRACT-CHAPTER 1 Pseudomonas aeruginosa is the primary cause of chronic endobronchial infections in the CF-lung lung, where it encounters selective pressures that include iron-limitation, antibiotics and immune system surveillance. This pathogen’s extraordinary adaptability arises in part from …
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Evolution of Pseudomonas aeruginosa in the Cystic Fibrosis Lung
<p>ABSTRACT-CHAPTER 1 Pseudomonas aeruginosa is the primary cause of chronic endobronchial infections in the CF-lung lung, where it encounters selective pressures that include iron-limitation, antibiotics and immune system surveillance. This pathogen’s extraordinary adaptability arises in part from …
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The effect of antibiotics on Pseudomonas aeruginosa biofilm production
… A highly resistant species is Pseudomonas aeruginosa, a nosocomial pathogen that produces a biofilm that enhances its resistance. This project examined the possibility of using bacteriocin, an internal protective toxin produced by some species of bacteria, as a potential treatment for …
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Modulation of airway mucin glycosylation by Pseudomonas aeruginosa pyocyanin
… with the respiratory pathogen Pseudomonas aeruginosa (PA). A favorable niche for PA growth is provided by an overabundance of mucus in CF airways. When compared to that of non-CF individuals, mucus of CF airways has been found to be enriched in sialic acid, especially in the form of the …
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Development of a flagellin-based multivalent vaccine against Pseudomonas aeruginosa
Although chronic Pseudomonas aeruginosa infection is the major cause of morbidity and mortality in cystic fibrosis (CF) patients, there is no approved vaccine for human use against P. aeruginosa. The goal of my research was to establish whether a multivalent vaccine containing P. aeruginosa type A …
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Effets de la pollution lumineuse sur l'écophysiologie de Microcytis aeruginosa
… Dans cette étude, une cyanobactérie, Microcystis aeruginosa , a été cultivée en turbidostat en absence et en présence d'éclairage nocturne tel qu'observé à la surface d'un lac urbain éclairé. Plusieurs mesures ont été réalisées des intervalles de deux heures sur trois périodes de 48h afin …
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Characterizing the advantages of diverse effector secretion in Pseudomonas aeruginosa
… this technique to effectors of the Pseudomonas aeruginosa H1-T6SS. This approach revealed that T6SS effector potency is dependent on the external environment and on the activity of simultaneously secreted effectors. Furthermore, I discovered intoxication by T6SS effectors could be …
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The genetics and phenotypes of Pseudomonas aeruginosa biofilm dispersal populations
… to the persistent colonization of Pseudomonas aeruginosa in the lungs, resulting in chronic pulmonary exacerbations. The ability to colonize CF patients’ lungs and other environmental habitats has been attributed to the large genome size of P. aeruginosa, and its ability to form biofilms. The …
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