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Showing 1 to 2 of 2 for “"ADMET prediction"”.

  1. Combining the Power of Attention Models and Many-objective Computational Intelligence Algorithms for Drug Design

    … metabolism, excretion, and toxicity (ADMET) pharmacokinetic properties of drug candidates in a later stage of drug design processes, where failure is most costly. To address this challenge, this research work aims to achieve three objectives. First, it explores the use of …

    brock Repository record for Combining the Power of Attention Models and Many-objective Computational Intelligence Algorithms for Drug Design (opens in a new tab)

  2. In silico-guided design, synthesis and antimicrobial activity of piperazine-linked 8-hydroxyquinoline-isatin hybrids

    … metabolism, excretion, and toxicity (ADMET) prediction platforms, SwissADME and pkCSM, to guide the selection of constructs with favourable pharmacokinetics and druglike properties. According to the docking studies, compounds 14a-c and 15a-c showed significant binding energy with …

    namibia Repository record for In silico-guided design, synthesis and antimicrobial activity of piperazine-linked 8-hydroxyquinoline-isatin hybrids (opens in a new tab)