Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"ADCY3"”.
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Using single-cell RNA sequencing to elucidate the biological basis of IBD and response to therapy
… variants in the adenylate cyclase (ADCY) genes ADCY3 and ADCY7, to understand the role of these IBD risk variants in immune cells. A trans-eQTL analysis performed in the immune cells of donors with carriage of the rare coding ADCY7 variant rs78534766 identified 65 unique trans-genes and enriched …
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Genomic profiling of response to $\textit{in vivo}$ immune perturbations
… effects. For example, a reQTL identified for ADCY3 specific to day 1 may be explained largely by high monocyte proportions at day 1 compared to other timepoints. Changes in cell composition present a significant challenge to interpreting reQTLs found through bulk sequencing of heterogeneous …