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Showing 1 to 1 of 1 for “"ADAM17 Protein"”.
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Molecular Players in Lupus: Leads from Proteomic Screens
… leukocytes by proteases ADAM10 and TACE (ADAM17) to abrogate macrophage anti-inflammatory signaling through Twist. I further find that β-catenin is dysregulated in SLE but the deletion of β-catenin in lupus-prone macrophages does not appreciably change disease course. Lastly, I find that …