Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"ACTIVATION OF ONCOGENES"”.
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Transcriptional regulation and genome structure
The regulation of gene expression is fundamental to the control of cell identity, development and disease. The control of gene transcription is a major point in the regulation of gene expression. Transcription is regulated by the binding of transcription factors to DNA regulatory elements known as …
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The role of anchorage in cell cycle control
… arrest or cell death, known as anoikis, due to activation of anchorage-dependent checkpoint mechanisms. Transformed cells alleviate these checkpoints, via activation of oncogenes and/or inactivation of tumour suppressors. In contrast, detachment of normal cells halts cell-cycle progression in …
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Identifying Protein Kinase Tbk1 As A Novel Inhibitor of Intestinal Tumorigenesis
… progresses in order to improve the strategies of CRC prevention and therapy. A major factor that drives the development of CRC is genetic mutations that lead to activation of oncogenes and inactivation of tumor suppressor genes in intestinal epithelial cells (IECs). In addition, the initiation …
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ΜΗΧΑΝΙΣΜΟΙ ΟΓΚΟΓΕΝΕΣΗΣ ΔΙΑ ΤΟΥ ΛΕΥΧΑΙΜΟΓΟΝΟΥ ΙΟΥ ΤΟΥ MOLONEY (MOMULV)
… FOLLOWING VIRUS INOCULATION. THE PHENOTYPE OF THESE TUMORS CORRESPONDS TO ALL THE STAGES OF T CELL DIFFERENTIATION. THE PROCESS OF ONCOGENESIS IN BOTH ITS EARLY AND LATE STAGES IS DUE TO PROVIRUS MEDIATES INSERTIONAL MUTAGENESIS. USING THE INTEGRATED PROVIRUS AS A MARKER WE HAVE IDENTIFIED …