Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"ACPA"”.
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Quantification and Molecular Characterization of Anti-citrulline Antibodies in Rheumatoid Arthritis
… Auto-antibodies against citrullinated proteins (ACPA) are present in approximately 60-75% of RA patients with 96% specificity. Although the importance of ACPA, both as a causative agent and diagnostic marker, has been established, the reactivities of single ACPA and the eptiopes are unknown. …
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Functional Similarity of Prd-Containing Virulence Regulators In Bacillus Anthracis
… anthracis </em>produces three regulators, AtxA, AcpA, and AcpB, that control virulence gene expression and are members of an emerging class of regulators termed “PCVRs” (Phosphoenolpyruvate-dependent phosphotransferase regulation Domain-Containing Virulence Regulators). AtxA controls expression …
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Arbitrarily-controllable programmable aperture light field cameras : design theory, and applications to image deconvolution & 3-dimensional scanning
… arbitrarily-controllable programmable aperture (ACPA) light field technology are presented. This new method of capturing light field data lends itself to an improved deconvolution technique dubbed "Programmable Deconvolution," as well as to 3D scanning and super-resolution imaging. The use & …
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Transglutaminase and peptidylarginine deiminase in the pathogenesis of autoimmune diseases
… with both anticitrullinated protein antibodies (ACPA) and auto-antibodies against the citrullinating enzyme, peptidylarginine deiminase (PAD). Previously, we have suggested that a complex between an enzyme and its modified substrate constitutes the neoantigen in autoimmune diseases. However, this …
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Markers and outcome measures in chronic immune mediated artrhritis: from association studies to prediction models.
… anti-citrullinated protein/peptide antibodies (ACPA) determination in rheumatoid arthritis (RA). ACPA is a very specific test for RA, but the specificity of this test may differ between study populations. Combinations of ACPA, RF and HLA-shared epitope testing are explored by different …
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The role of Human Endogenous Retrovirus K10 (HERV-K10) in the pathogenesis of rheumatoid arthritis via molecular mimicry
… Fc, and anti-citrullinated protein antibodies (ACPA) to citrullinated autoantigens such as fibrinogen. Although RA pathogenesis has not been elucidated, genetic predisposition, environmental insults and viral pathogens are considered contributory factors. Human endogenous retrovirus K10 …
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Microwave-Accelerated Synthesis of Isoxazole Inhibitors of The System Xc- Transnporter
… propionic acid (ACPA) has been identified as a promising lead in the search for potential selective glutamate binding protein ligands due to its high efficacy and specificity. In previous work from our group, it was found that isoxazole analogs bearing a hydrozone …
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Microwave-Accelerated Synthesis of Isoxazole Inhibitors of The System Xc- Transnporter
… propionic acid (ACPA) has been identified as a promising lead in the search for potential selective glutamate binding protein ligands due to its high efficacy and specificity. In previous work from our group, it was found that isoxazole analogs bearing a hydrozone …
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The Impact Of The External Environment On Person-Environment Fit In The Selection Of New Housing Professionals
… interest in student affairs competencies (ACPA & NASPA, 2010) as well as the literature around person-environment fit as a factor for satisfaction and retention of new professionals. The work of Werbel and colleagues (Werbel & Gilliland, 1999; Werbel & DeMarie, 2005) provided a useful model …
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Studio sul lessico del mare in volgare siciliano
… (ASP) e l’Archivio del Comune di Palermo (ACPa); ii) conservati presso la National Library of Malta e gli Archives of the metropolitan Cathedral in Mdina. Nel secondo capitolo si illustra la struttura delle schede lessicografiche, per una parte modellata sulla scheda-tipo adottata dal VSM e …
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Fisura labio-palatina : estudio clínico-epidemiológico y valoración de calidad de vida
… europeas y mundiales de fisurados (Eurocran y ACPA): número mínimo de 30-50 casos incidentes tratados por año, edades máximas para queiloplastia -6 meses- y palatoplastia -18 meses-. En niños fisurados de 4 a 7 años, la percepción de la CVRS autopercibida medida con el cuestionario kiddy-KINDL …
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Proteomics: A close encounter with rheumatology
… antilichamen tegen gecitrullineerde proteïnen (ACPA) in RA. Inderdaad, bijkomend in hoofdstuk 2 toonden we aan dat de aanwezigheid van autoantilichamen tegen gecitrullineerde fragmenten van vimentine specifiek was voor RA. Deze bevindingen wezen op een nieuw concept in de ontwikkeling van …