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Showing 1 to 20 of 31 for “"ACK"”.

  1. The role of ACK in regulating the Vav family proteins

    Ip, Chi Yeung MarcoUniversity of Cambridge2022

    … non-receptor tyrosine kinase effector of Cdc42, ACK, has been identified as an oncogene. Aberrant expression and mutations of ACK have been found in many types of cancer, such as prostate, breast and pancreatic. Clinically, ACK mutants or overexpression correlates with poor prognosis. Recent …

    cambridge Repository record

  2. MAC Layer DATA/ACK Handshake in the Hybrid VLC-RF System

    Zhang, JunyiRice University2016

    … would cause problems for the MAC layer DATA/ACK handshake. The acknowledgements for VLC packets have to be transmitted via ra- dio. Because of the Wi-Fi channel's contention based random access, the transmission will be delayed and degrades the performance of the legacy Wi-Fi, especially when …

    rice Repository record

  3. Investigating the Functional Interaction between RhoGDI Family Proteins and Activated Cdc42 associated-kinase (ACK)

    Binti Ahmad Mokhtar, Ana MasaraUniversity of Cambridge2020

    ACK is a non-receptor tyrosine kinase and an effector protein for Cdc42. ACK has been implicated in carcinogenesis events especially in promoting cell migration and invasion, indicating a need for a fuller understanding of the cellular roles of ACK both in normal and pathological conditions. A …

    cambridge Repository record

  4. Characterising the effects of ACK-mediated phosphorylation on the Class IA PI3-Kinase regulatory isoforms

    Hodder, SamanthaUniversity of Cambridge2025

    Activated Cdc42-associated kinase (ACK), a non-receptor tyrosine (Tyr) kinase, was the first effector discovered for the small GTPase Cdc42. ACK is emerging as an important feature of the cancer landscape and thus, is a promising potential target for the treatment of many malignancies. ACK …

    cambridge Repository record

  5. The regulation of the oncogenic STAT transcription factors by the non receptor tyrosine kinase and Cdc42 effector ACK

    Corry, JessicaUniversity of Cambridge2022

    Activated Cdc42-associated kinase (ACK) is a Rho family effector that is widely implicated in cancer, yet not currently pharmacologically inhibited in the clinic. Through relationships with the androgen receptor in prostate cancer and the oestrogen receptor in breast cancer, ACK regulates …

    cambridge Repository record

  6. Dissecting the Function of Ack Family Kinases in Drosophila Through Understanding Their Interactions with Dock and CDC42

    Abdallah, Abbas M

    purdue-thes Repository record

  7. Assembly of nuclear dimers of the PI3K regulatory subunits underpins the proliferative activity of Activated Cdc42-associated Kinase, ACK

    Fox, MillieUniversity of Cambridge2021

    ACK is an oncogenic non-receptor tyrosine kinase associated with poor prognosis in human cancers. ACK promotes proliferation, in part, by contributing to the activation of Akt, the major PI3K effector. The work presented here demonstrates that ACK also regulates proliferation via interactions with …

    cambridge Repository record

  8. Simulation Study of an ADSL Network Architecture: TCP/IP Performance Characterization and Improvements using ACK Regulation and Scheduling Mechanisms

    Phanse, Kaustubh SuhasVirginia Tech2000

    … performance in presence of a new protocol stack (TCP/IP over PPP and ATM) being promoted for one of the ADSL network architectures. Using extensive simulations, we verify the adverse effects of asymmetric links on the performance of TCP and additional throughput degradation caused by the …

    vt Repository record

  9. Expanding the genetic code of a mouse

    이, 순장2015

    … Chin, 2012) In this study, I used Acetyllysine(AcK) as unnatural amino acids, N? -acetyl-lysyl-tRNA synthetase (AcKRS) as AcK-tRNA synthetase, pyrrolysyl-tRNA(PylT) as tRNA from Methanosarcina mazei (Mukai et al., 2008). Amber codon was inserted in GFP that is role of reporter gene. AcKRS …

    ajou Repository record

  10. Indian comics as public culture

    Das, Abhimnanyu, S.M. Massachusetts Institute of TechnologyMassachusetts Institute of Technology2009

    The Amar Chitra Katha (ACK) series of comic books have, since 1967, dominated the market for domestic comic books in India. In this thesis, I examine how these comics function as public culture, creating a platform around which groups and individuals negotiate and re-negotiate their identities …

    mit Repository record

  11. Attacking Ras-driven cancers: Engineering a peptide inhibitor for Cdc42

    Tetley, George Jeremy NormanUniversity of Cambridge2018

    … region (GBD) of the Cdc42-specific effector ACK, which is 42 amino acids long and binds with 40 nM affinity. The aim of this work was to find a peptide which exhibits similar effects in reversing oncogenic characteristics in cells but with more promising therapeutic properties: for example, a …

    cambridge Repository record

  12. Protecting 802.11-Based Wireless Networks From SCTS and JACK Attacks

    Zhang, Zhiguo

    … Error-prone wireless networks afford an attacker considerable flexibility to exploit the vulnerabilities of 802.11-based mechanism. Two of most famous misbehaviors are selfish and malicious attacks. In this thesis we investigate two attacks: Spurious CTS attack (SCTS) and Jamming ACK attack …

    uno Repository record

  13. Characterization of the genes and gene products of the acetate-activating enzymes and a novel iron-sulfur flavoprotein from Methanosarcina thermophila strain TM-1

    Latimer, Matthew T.Virginia Tech1993

    … directly upstream of the acetate kinase gene (<i>ack</i>). The two genes were sequenced, along with a third Open Reading Frame (designated <i>orfY</i>). The <i>orfY</i> gene appears to encode a novel protein whose physiological function has yet to be determined.

    vt Repository record

  14. Performance Evaluation of Token Control Networks

    Cheng, Wu-YehUniversity of Illinois at Urbana-Champaign2014

    … simulation. The performance of stop-and-wait ACK/NAK ARQ schemes are evaluated. Trade-offs between average access delay and average end-to-end throughput are discussed.

    uiuc Repository record

  15. A Reconfigurable Random Access MAC Implementation for Software Defined Radio Platforms

    Anyanwu, Uchenna KevinVirginia Tech2012

    … access MAC implementations: Aloha with Explicit ACK and Aloha with Implicit ACK. A point-to-point link was tested with our protocol and then this link was extended to a 3-hop (4 nodes) network. To improve our protocols' efficiency, we implemented carrier sensing on the FPGA of the USRP E100, an …

    vt Repository record

  16. Comparison of modified Riks/Wempner and homotopy methods

    Sunku, B. S.Virginia Polytechnic Institute and State University1991

    A structured program has been developed to track the equilibrium path of geometrically nonlinear space structures by the modified Riks/Wempner method. The sparse normal flow code in 'HOMP ACK' is used for tracking the equilibrium paths by the homotopy method. Two subroutines were written as …

    vt Repository record

  17. The design and implementation of a congestion control plane

    Narayan, Akshay(Akshay Krishna)Massachusetts Institute of Technology2019

    … like mTCP-on-DPDK-summarizes information about packet round-trip times, receptions, losses, and ECN via a well-defined interface to algorithms running in the off-datapath Congestion Control Plane (CCP). The algorithms use this information to control the datapath's congestion window or pacing …

    mit Repository record

  18. ‘Rise Up Dead Man and Fight Again’: Reviving and Defining Mumming in County Fermanagh

    Finnegan-Kessie, ThreaseNational University of Ireland Maynooth2015

    … the tradition in Fermanagh: The Aughakillymaude (ACK-LAMAD) Mummers. This thesis explores how mumming has been redefined by both the mummers and the audience. Throughout the thesis, it is argued that while social practices are viewed as possessing longevity and immutability both time and context …

    maynooth Repository record

  19. A critical discussion of the twelve-tonal idiom of Anton Webern and criticism of its assessmant by some natable theorists

    Everson, CromwellCollege of Music1973

    … spirits to travel this razor edge. Lesser ones 1 ack the requisite inner certainty. Indeed Webern never pandered to popular taste. iii Every tone he wrote was dictated to by musical necessity ·and logic. No other composer has shown such iron consistency in the development of his art as Webern has. …

    cape-town Repository record

  20. A critical discussion of the twelve-tonal idiom of Anton Webern and criticism of its assessmant by some natable theorists

    Everson, CromwellCollege of Music1973

    … spirits to travel this razor edge. Lesser ones 1 ack the requisite inner certainty. Indeed Webern never pandered to popular taste. iii Every tone he wrote was dictated to by musical necessity ·and logic. No other composer has shown such iron consistency in the development of his art as Webern has. …

    cape-town Repository record

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