Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"ABCG5"”.
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The Role of ABCG5/G8 in Sterol Homeostasis
THE ROLE OF ABCG5/G8 IN STEROL HOMEOSTASIS
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HEPATIC LIPID METABOLISM: THE ROLES OF ACAT2 AND ABCG5/G8 IN THE DEVELOPMENT AND PREVENTION OF DISEASE
… (ATP) Binding Cassette transporters G5 and G8 (ABCG5/G8 or G5G8) form an apical membrane obligate heterodimeric protein complex that transports intracellular free sterols to bile or the intestinal lumen. Data are presented to show that transgenic over-expression of G5G8 does not affect the NAFLD …
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The Roles of ATP-Binding Cassette Transporters G5 and G8 in Liver X Receptor-Mediated Sterol Trafficking
… , the ATP-binding cassette (ABC) transporters Abcg5 and Abcg8, is required for the increase in sterol excretion, the decrease in fractional cholesterol absorption, and the increase in fecal neutral sterol excretion associated with LXR agonist treatment. Mice lacking ABCG5 and ABCG8 (G5G8-/- …
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MECHANISMS OF INTESTINAL CHOLESTEROL ABSORPTION AND TRANSPORT IN MOUSE THORACIC LYMPH DUCT LIPOPROTEINS
The metabolic fate of newly absorbed cholesterol and phytosterols is orchestrated through the sterol transporter, adenosine triphosphate-binding cassette transporter G5/G8 heterodimer (G5/G8), and the cholesterol esterifying enzyme, acyl coenzyme A:cholesterol acyltransferase 2 (ACAT2). We …