Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"AB42"”.
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Understanding protein misfolding diseases through the development of biophysical methods
… in their ability to inhibit the aggregation of Ab42, characterising the molecular mechanisms of inhibition and validating our strategy in an animal model of AD. We conclude by discussing the potential impact and expected challenges of our systematic in vitro and in vivo approach, as we aim to …
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On the phenomenon and potential applications of pulsed laser-reshaped silver nanoparticles embedded in soda-lime glass
This thesis presents studies on a novel ‘meta-material’ as a potential candidate to replace the traditional Electro-Optic crystals (GaP, ZnTe) used in ultrashort bunch monitors for electron/positron accelerators. This study is aimed at showing the linear and non-linear optical properties of such …
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Engineering properties and structural behaviour of high strength reinforced concrete beams
High Strength Concrete (HSC) has become a viable alternative to lower strength concrete. However, its utilisation is increasing faster than the development of suitable design recommendations. This is because limited and diverse investigations have been carried out concerning engineering properties …
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Small Molecule Binding to Disordered Proteins
The human proteome includes many proteins that are entirely disordered or contain long disordered regions. Although these proteins are linked with many diseases, there are currently no clinically-approved drugs that have been shown to target these proteins in their monomeric forms. In fact, …