Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"AAV-PHP.eB"”.
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AAV9-mediated (Pro)renin Receptor Antagonism Reduces High Fat Diet Induced Hyperglycemia and Hepatic Steatosis in Mouse Model of Non-alcoholic Fatty Liver Disease
… delivered by adeno-associated virus, serotype 9 (AAV9) vector via systemic route, based on the findings of a prior experiment in this study. Here we validated AAV-PHP.eB and AAV9 in Neuro-2A cells, and confirmed AAV-PHP.eB and AAV9 expression in the brain and in non-CNS tissues. In addition, we …
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Prime Editing as a Potential Therapeutic Intervention for Generalized Epilepsy with Febrile Seizures Plus (GEFS+): From Gene Editing to Functional Recovery
… gene associated with Generalized Epilepsy with Febrile Seizures Plus (GEFS+), a severe neurodevelopmental disorder characterized by hyperthermia-induced seizures and premature mortality. Using an intein-split prime editor delivered via neuron-specific adeno-associated viral vectors (AAV-PHP.eB), …