Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"A990 - Medicine & dentistry not elsewhere classified"”.
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A feasibility study of chemosensitivity testing in primary cultures from malignant gliomas, and analysis of drug resistance mechanisms
… the primary culture. Every tumour is unique phenotypically and genotypically and several factors induding clinical characteristics, radiological features and conventional histology might act as pointers to this uniqueness. Proteins ktown to be associated with drug resistance in other tumours …
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The significance of strain diversity in the epidemiology of Camplobacter jejuni gastrointestinal infections
… undertakert Isolates were characterised by phenotype, using heat stable antigen serotype, bacteriophage type and biotyping methods. Isolates were also genotyped by restriction fragment length polymorphism analysis of genomic DNA, using a 16S rRNA gene probe, a random-cloned DNA sequence probe, …
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Functional, Structural and Molecular Alterations in the Heart and Kidney During Diabetes Mellitus
… ECM. Molecular derangements underlying this phenotype included increased TGFβ1 transcription and activity, recapitulation of foetal gene phenotype atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP) with marked hypertrophy, underscored by caspase-3 mediated cell apoptosis. Electron …
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The Influence of Culture on the Views of Black African/African-Caribbean Men Living In the UK Towards Cancer
… prevention and early detection strategies may not be sensitive to UK-based black men views, affecting their awareness of risk factors and early detection services. An evidence based understanding about black men’s views towards cancer is needed to effectively target cancer prevention …
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The Role of Facilities Management in the Control of Healthcare Associated Infections (HAI)
A growing body of evidence now exist, which suggests that Healthcare Associated Infections (HAI) are a major cause of morbidity and mortality. There is, however, a paucity of empirical knowledge and evidence-base of the role of Facilities Management (FM) in the control of HAI. Therefore, the main …
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Historical Development and Contemporary Dilemmas of a Police Surgeon
… investigation the concept of Clinical Forensic Medicine became established. The formation of the Faculty of Forensic and Legal Medicine in 2006 with the objectives of promoting the advancement of education and knowledge in forensic and legal medicine and ensuring the highest professional …
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The Identification and Classification of Sharp Force Trauma On Bone Using Low Power Microscopy
… The data suggests that consistent force was not achieved and the resultant marks on the bones made by the same knife had wide variation in their appearance and depth. The classification criteria tested did not provide discrete identification of knife blades from the assessment of kerf …
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Deconstructing Clinical Practice and Searching for Scientific Foundations: Examining decision-making scaffolds underpinning intervention choices by speech and language therapists
… practice decisions. This suggests practice may not be scientific. Furthermore, unscientific practice may be represented by the use of pseudoscientific and / or non-scientific therapies. Aim: The aim of this research was to explore professional knowledge and decision-making scaffolds in SLT …
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17-AAG and sihsp90α combinational therapy as a novel anti-cancer approach
… The use of 17-AAG concomitant with sihsp90α did not demonstrate synergistic anti-tumour effects in glioblastoma in vitro. Furthermore, the application of siRNA as an alternative to small-molecule inhibitors in the treatment of human disease has shown therapeutic potential. However, a major hurdle …
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Children's Nurses' Perceptions of Continuous Professional Development
Continuous Professional Development (CPD), sometimes referred to as Lifelong Learning or Continuing Education, is a relevant and important issue for nurses, doctors and other professionals. However there is little specific literature that demonstrates children's nurses' perceptions about CPD. This …
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Development of Liposome Drug Delivery Systems for Anti-Glioma Therapy
This study aims to investigate the potential of ethanol-based proliposomes in generating paclitaxel-loaded liposome delivery in vitro, by employing various phospholipid compositions. Liposomes prepared using ethanol-based proliposome method successfully generated multilamellar vesicles. Three …
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Pregnancy outcome in South Asian women: Factors affecting diet and nutrition
… between South Asian women who did and did not take iron supplements during pregnancy but further potential confounding variables would need to be considered before any causal link could be identified. The dietary nutrient intake analysis of non-pregnant South Asian women found that iron, …
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Quality versus Quantity? A time use study of father-mother pairs with a disabled preschool child
Time use studies are an effective way of finding out more about individuals’ daily lives and when used with semi-structured interviews can provide a form of participant observation. Large multinational studies have been performed over the past 40 years providing comprehensive data on general …
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Rethinking postnatal care: A Heideggerian hermeneutic phenomenological study of postnatal care in Ireland
… of postnatal care: ‘Becoming Family’, ‘Seen or not seen’, ‘Saying what matters’, ‘Checked in but not always checked out’ and ‘The struggle of postnatal fatigue’. The original insights from this research clearly illuminate the vulnerability women face in the days following birth. A further …
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DNA Persistence and Preservation Following Environmental Insult
… as possible (even if immediate storage is not possible) may be beneficial for DNA persistence. Seasonal variation in DNA persistence was observed due to maggot mass growth which increases carcase decomposition and ultimately effect on DNA persistence. Controlled incubation experiments were …
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Role of Cell Death Regulatory Genes and Radiation Response in Pancreatic Adenocarcinomas
… leads us to hypothesize that K-ras mutant phenotype status in pancreatic turnours will alter the expression of the RII and PAR-4 genes, and would further dysregulate growth inhibitory and apoptotic processes. In this study, the majority of pancreatic turnours showed down-regulation of RII and …
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Perceptions of the Midwife’s Role: A Technoscience Perspective.
… it draws on the work of Donna Haraway. Haraway’s notion of ‘situated knowledges’ provides the opportunity to locate the views of women and midwives. This provided the opportunity to utilise her notions of ‘modest witness’, ‘cyborg’, ‘goddess’, ‘material-semiotic’ and connect to their perceptions. …
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Single Nucleotide Polymorphisms:Characterisation and Application to Profiling of Degraded DNA
… that two individuals having identical genotype profile was found to be very low, 3.058 x 10-25. The combined power of discrimination was found to be 0.999999999. This indicated that the selected SNPs met the parameters needed for forensic application. The SNPs genotype sensitivity gave …
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An evaluation of cardiac services in four hospitals in Lancashire for patients with ischaemic heart disease
… cases and 200 cases of patients suspected, but not eventually diagnosed as MI. Patients from this sample who agreed to co-operate provided data at six-weeks and six-months post infarction. A questiolmaire was also filled in by the GP at six-months post infarct. When appropriate Lancashire …