Global ETD Search
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Showing 1 to 2 of 2 for “"A35R"”.
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Effects of Modified Vaccinia Virus Ankara Expressing Mesothelin and the Poxvirus Immunoregulatory A35R gene in the Treatment of Murine Pancreatic Cancer
… protein expression. Our hypothesis was that the A35R[delta] recombinant virus would be more efficient at stimulating the immune system and better protect against tumors caused by the Panc02 pancreatic adenocarcinoma cell line. MVA was found to both kill and replicate in Panc02 cells, showing it …
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Examination of the role of early viral protein expression in MVA-induced NF-κB activation
… these cells. Three viral genes (C11R, E7R, and A35R) have been identified whose silencing can prevent MVA-induced ERK1/2 activation, which occurs upstream of NF-κB activation. The product of C11R, a viral growth factor protein, is capable of inducing ERK1/2 and NF-κB activation in the host 293T …