Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"9p21 locus"”.
-
Characterization of 𝘈𝘵𝘩𝘴𝘲1, an Atherosclerosis Modifier Locus on Mouse Chromosome 4:
… a coronary heart disease susceptibility locus on chromosome 9p21 identified by genome-wide association studies in humans. In this study we have used congenic mice that were previously constructed to isolate 𝘈𝘵𝘩𝘴𝘲1, an atherosclerosis susceptibility locus identified in a cross between …
-
Clinicopathological and molecular characterization of gastroesophageal junction (GEJ) adenocarcinoma before age of 40 years
… (FISH) DNA probe set specific for the locus specific regions 9p21 (p16), 20q13.2 and Y chromosome. We evaluated 663 patients with GEJ adenocarcinoma and further divided them into 2 age-groups of <or= 40 and >or= 50 years, rispectively. FISH with selected DNA probe for Y chromosome, …
-
Rational drug combinations to selectively target 9p21-deleted bladder cancer
… the synthetic lethal vulnerabilities exposed by 9p21 loss in BLCA, the most common copy-number alteration in this tumor. Previous studies have investigated 9p21 loss across several cancer types and identified PRMT5 and MAT2A as synthetic lethal interactions in this context. Consequently, PRMT5 …