Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"9p"”.
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Prognostic Significance of Chromosome 9p Deletion in Clear Cell Renal Cell Carcinoma
… has been explored in several studies. Chromosome 9p deletion was reported as an independent prognostic factor in clear cell subtype (ccRCC). The findings from these studies initially appeared promising however they were of limited clinical applicability due to lack of standardisation of molecular …
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Identifying the Role of Transcription Factor RFX3 in 9PDeletion Syndrome
9p deletion (9p-) syndrome is primarily characterized by intellectual disability, developmental delays, and autism. This project investigated how much of the neuronal phenotypes of 9p- syndrome could be attributed to RFX3, a transcription factor and autism risk gene. Bulk RNA-seq data of …
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Acute Lymphoblastic Leukemia in Adolescents and Young Adults in Finland
… Also deletions and instability of chromosome 9p were screened in ALL patients. In addition, patients with other hematologic malignancies were screened for 9p instability. aCGH data were also used to determine a gene set that classifies AYA patients at diagnosis according to their risk of …
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A Molecular Cytogenetic Profile of the Chronic Myeloproliferative Disorders
… Acid (DNA) probes sequenced to regions along 9p were selected. These probes were then applied to CMPD patient samples with both normal and abnormal karyotpyes, focusing on the region containing Janus Kinase 2 Gene (JAK2) at 9p24.1. In this ongoing study 18% of patients have been shown to carry …
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Klinische Bedeutung von immunhistochemischen und zytogenetischen Risikofaktoren beim Mantelzell-Lymphom
… die häufigsten Deletionen in –1p, -6/6q, -8p, -9/9p, -11/11p, -13/13p, 14/14q und –17/17p zu finden waren. Der Bruchpunkt 1q32 war mit blastischer Zytomorphologie assoziiert und Patienten mit Deletionen in 1p, 9/9p und 1q zeigten einen signifikant höheren Proliferationsindex als die …
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Penerapan strategi Marketing Mix pada Biro Jasa Transportasi Safara Tour Travel Bojonegoro Jawa Timur
… marketing mix Penerapan strategi marketing mix “9P” pada Safara Tour Travel Bojonegoro berjalan dengan baik, berfokus pada strategi harga. dan marketing mix terdiri atas strategi produk (membuat produk jasa pelayanan dan pengiriman, menciptakan kemasan dan target pasarnya), strategi harga …
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Enhancing Early Detection of Oesophageal Squamous Cell Carcinoma Through Shallow Whole-Genome Sequencing and Non-Endoscopic Sponge Sampling
… specific alterations in chromosome arms 2q, 3q, 9p, and 11q, along with the GWIS, as significant predictors of OSD and early OSCC. A logistic regression model integrating these CNA-based biomarkers achieved a cross-validated area under the curve (AUC) of 0.925 (95% CI: 0.913-0.936), with …
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Single nucleotide polymorphism array analysis in copy number variant detection: assessment of its feasibility in the diagnostic setting
… syndrome, Wolf-Hirschhorn syndrome, tetrasomy 9p, and a susceptibility locus for neurodevelopmental disorders due to a deletion of chromosome 1q21.1. This indicated a 26% detection rate in this cohort. In addition, three variants of unknown significance (VOUS) were detected. The aim of this …
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Genetische Aberrationen mit einem Wachstumsvorteil in frühen Präkanzerosen des Urothels der Harnblase
… showed mainly a loss of the chromosomal region 9p21 in proliferating cells, like expected from FISH results. Other chromosomal aberrations, depicted in dysplasia cells, were deletion of chromosome 9 and 13q as well as amplifications of the chromosomes 9p, 12p, 17q, 18p, 22, X and Y. In this …
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Abnormalities affecting tyrosine kinase signalling in atypical myeloproliferative disorders
… eg. the activating JAK2 V617F mutation and 9p aUPD. I have undertaken a screen using Affymetrix 50K SNP arrays for regions of acquired isodisomy as a means to identify genomic regions that may harbour novel oncogenes in different subgroups of MPD patients. Large tracts of homozygosity …
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Formation of C 3 and C 2 in cometary comae
… 4 Kometen C/2001 Q4 (NEAT), C/2002 T7 (LINEAR), 9P (Tempel 1) and C/1995 O1 (Hale-Bopp) untersucht diese Arbeit welche Kombination der in der Literatur vorgeschlagenen Elternmoleküle C4H2 (Diacetylen), CH2C2H2 (Allene), CH3C2H (Propin), C2H4 (Ethen) und der beobachteten Elternmoleküle C2H2 und …
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Subtelomere Chromosomenveränderungen mittels quantitativer Real-Time PCR bei Patienten mit mentaler Retardierung und normalem zytogenetischem Chromosomensatz
… und 10 Duplikationen (1p, 2p, 6p, 7p, 7p, 7p, 9p, 10q, 10q und 19q), wobei drei der Patienten sowohl eine Duplikation als auch eine Deletion trugen. Bei sechs der Patienten stehen die subtelomeren Aberrationen in kausalem Zusammenhang mit dem Phänotyp der mentalen Retardierung, diese zeigten …
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Genetic analysis of squamous cell carcinoma of the head and neck
… of DNA were identified on chromosome 3p, 4p, 8p, 9p, 11 q, 13q and 18q and frequent gains on chromosomes 2q, 3q, 5p, 7q, 8q, 9q and 11q. The histologically normal mucosa did not show chromosomal abnormalities within the cells analysed. Therefore, if molecular abnormalities were present in the …