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Showing 1 to 1 of 1 for “"8-chloro-adenosine"”.

  1. Mechanism-Based Strategies to Enhance The Actions of A

    … The transcription and translation inhibitor 8-Chloro-Adenosine (8-Cl-Ado), currently in clinical trials, is metabolized into its cytotoxic form 8-Cl-ATP causing a parallel decrease of the cellular ATP pool. Treatment with 0.5 µM 17-AAG for 8 hours resulted in the induction of all HSP transcript …

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