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Showing 1 to 11 of 11 for “"8-OHdG"”.
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Thymoquinone decreases oxidative DNA damage (8-OHdG) in DMBA treated female Sprague Dawley rats
… (GSH) levels and 8-hydroxydeoxyguanosine (8-OHdG). Thymoquinone (TQ), the main active ingredient of Nigella sativa, or Black seeds, is used in the Middle East for treatment of several diseases, especially cancer. The aim of my research was to investigate the role of thymoquinone in improving …
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Mitochondriale DNA Mutationen und Untersuchungen zum oxidativen Stress beim idiopathischen Parkinsonsyndrom
… (z.B. Komplex I-Mangel, erhöhte Eisen- und 8-OHdG Werte im Gehirn), aber bis heute gibt es keine eindeutigen Hinweise, wodurch es zur Entstehung der Krankheit kommt. Da es am wahrscheinlichsten ist, dass die Krankheit multifaktoriell bedingt ist, könnten auch Mutationen der mitochondrialen DNA …
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Modificación del daño oxidativo en un grupo de ciclistas tras consumir ácido docosahexaenoico a distintas dosis
… sobre lípidos a nivel plasmático (MDA) y ADN (8-OHdG en orina). Con respecto a la concentración de 8-OHdG en orina se obtuvieron varias resultados: primero, la excreción urinaria de 8-OHdG en relación al peso del ciclista resultante de la prueba de esfuerzo se incrementó significativamente en la …
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DNA damage in paediatric obesity: a promoter and predictor of cancer in adulthood
… (qPCR) and urinary 8- hydroxyguanosine (8-OHdG) via EIA. The results from this study indicate obesity to be concurrent with increased inflammation and vitamin D deficiency in this cohort of participants. In addition, obesity was associated with increased oxidative DNA damage (8-OHdG) in …
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Endocrine, cellular and molecular effects of diabetes mellitus on male fertility
… adduct 7,8-dihydro-8-oxo-2'-deoxoguanosine (8-OHdG). Significantly higher levels of 8-OHdG were found in sperm from diabetic compared to non-diabetic men, suggesting that oxidative stress is an important factor in diabetes-asociated sperm DNA damage.<br/><br/>Sustained exposure to …
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Evaluation of suboptimal health status and prospective levels of oxidative stress biomarkers and angiogenic growth mediators with placental anatomy and pathology in normotensive and preeclamptic births
… [8-epi-PGF2α], 8-hydroxy-2-deoxyguanosine [8-OHdG] and total antioxidant capacity [TAC]) were evaluated across the 4-time sampling periods (10-20, 21-31, 32-42 weeks, and 48 hours-2 weeks postpartum) using ELISA. Placenta tissues were collected after delivery and examined for macroscopical, …
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Efecto de una bebida antioxidante sobre marcadores de estrés oxidativo y riesgo cardiovascular en pacientes con Síndrome Metabólico
… oxidativo: 8-Hidroxi-2-desoxiguananosina (8-OHdG), Grupos carbonilo, Hisoprostanos, LDL oxidadas, Cociente GSH/GSSG. Parámetros bioquímicos: Glucosa, Colesterol total, HDL colesterol, LDL colesterol, Triglicéridos, Proteínas totales, Albúmina, Acido Úrico, Homocisteína, Urea, Proteína …
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An Evaluation of exposures to respirable particulates, environmental PM2.5, PAHs and metal compounds in Western Australia
… (MDA) and 8-hydroxy-2’deoxyguanosine (8-OHdG) which are oxidative stress markers indicative of cellular and DNA damage. A positive correlation between urinary Ni and Co exposure and oxidative stress markers among refinery workers was established. This finding has implications for …
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Análisis de la influencia del tipo de lípidos constituyentes de fórmulas parentales en el estado nutricional, inflamatorio y oxidativo del paciente crítico
… con elevados marcadores de estrés oxidativo (8-OHdG, isoprostanos) e inflamación (IL-1𝛽������, IL-6). Tras 7 días de tratamiento, no se encontraron diferencias estadísticamente significativas entre los dos grupos en la mayoría de los parámetros analizados, incluyendo la evolución clínica global, …
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Metals and polycyclic aromatic hydrocarbons in environmental matrices of the Fleet Lagoon, UK and toxicological investigations using the marine polychaete Hediste diversicolor.
… cytochrome P450, superoxide dismutase as 8-OHdG adducts post exposure were identified. Additionally, potential inhibition of both GST and CYP450 were observed during the assimilation phases for all exposure groups. Energetic alterations following exposure were identified in all exposure …
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Protective effects of regular exercise and Korea red ginseng against high-fat diet-increased renal injury in ᴅ-galactose-induced aging rats
… for 9 weeks. Immunohistochemical staining for 8-OHdG (a specific marker of oxidative DNA damage) and CMLs (a marker of both glycation and lipoxidation reactions) revealed that GAL-treated rats fed a HFD showed aggravated renal injury associated with more pronounced renal AGEs/ALEs formation and …