Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"661W"”.
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Steroid induced neuroprotection of damaged photoreceptor cells
… in which Norgestrel worked. To this aim, the 661W cone photoreceptor-like cell line and ex vivo retinal explanting was utilised. We found that Norgestrel induces a increase in neuroprotective basic fibroblast growth factor (bFGF) with subsequent downstream actions on the inhibition of glycogen …
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Study of the role of miR-204 in photoreceptor development
… i.e. medaka fish) and <i>in vitro</i> (661W cell line) systems. I found that, the gain-of-function of miR-204 led to an earlier exit of photoreceptor precursors from cell cycle and to a concomitant earlier ‘fate determination’, which in turn resulted in earlier onset of photoreceptor …
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Inflammasome upregulation and activation in photoreceptors of type 2 diabetes and N-methyl-N-nitrosourea models is attenuated by Wedelolactone
… components and activation of this pathway in 661W photoreceptor cells.<br/><br/>In vitro, 661W photoreceptor cells were treated with exogenous DNA (poly(dA:dT)) to determine the role of the AIM2 inflammasome in cell death. In vivo, chemical photoreceptor degeneration was induced via …
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Redox biology in retinal degeneration
… mouse model. In the current study, using the 661W cone photoreceptor-like cell line and retinal explants from rd10 mice, we demonstrated that ROS are used by Norgestrel to enhance cell survival. We found that such stimulation of pro-survival ROS levels occurs very rapidly, and is both PGRMC1 …