Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"64Cu-ATSM"”.
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Occupational dose assessment of 64Cu-ATSM in a veterinary setting
64Cu-ATSM is an emerging radiopharmaceutical for diagnostic use in Positron Emission Tomography (PET) and has potential utility for radiation therapy but to date there are no studies that assess the occupational doses delivered to workers in either a hospital or veterinary environment. This study …
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Evaluation of 64Cu-ATSM in cell culture for potential use as a radiotherapy agent
… and more effective means to treat these tumors. 64Cu-diacetyl-bis(N4-methylthiosemicarbazone) (64Cu-ATSM) has shown clinical usefulness in imaging and experimental radiotherapy of solid state tumors due to its ability to concentrate in hypoxic tissue regions and emit radiations of multiple types, …
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PRECLINICAL PET IMAGING FOR TUMOUR CHARACTERIZATION: FOCUS ON HYPOXIA AND INFLAMMATION
… recently developed, [18F]FAZA and [64Cu]ATSM at two different times, using PET and autoradiography. In parallel, an in vitro evaluation of specific hypoxic markers such as carbonic anhydrase IX and cupper transporters (Ctr-1 and ATP7B) was performed. In FaDu model we confirmed the …
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64^Cu-bis(thiosemicarbazone) Complexes for Delineating Myocardial Hypoxia
… perfused hearts. While the lead compound Cu-ATSM has been widely investigated, a library of related Cu-BTSC complexes exist which may have better pharmacokinetics and selectivity for application in cardiology. We employed isolated ventricular myocytes and isolated perfused hearts to screen a …
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64Cu-bis(thiosemicarbazone) complexes for delineating myocardial hypoxia
… perfused hearts. While the lead compound Cu-ATSM has been widely investigated, a library of related Cu-BTSC complexes exist which may have better pharmacokinetics and selectivity for application in cardiology. We employed isolated ventricular myocytes and isolated perfused hearts to screen a …