Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"6-hydroxymelatonin"”.
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Protection of Pifithrin-α and Melatonin against Doxorubicin-Induced Cardiotoxicity.
… effects of melatonin and its metabolite 6-hydroxymelatonin on doxorubicin-induced cardiac dysfunction were evaluated in an isolated perfused mouse hearts and <em>in vivo</em> doxorubicin-treated mice. While perfusion of mouse hearts with 5 μM doxorubicin for 60 min resulted in a 50% …
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Investigation of DNA methylation at the promoter region of the aralkylamine N-acetyltransferase (AANAT ) gene in South African children with Autism Spectrum Disorder
… system (case n=19, control n=20). Urinary 6-hydroxymelatonin sulphate (6-OHMS) was quantified with an enzyme-linked immunosorbent assay (case n=4, control n=4). The 6-OHMS investigation was complemented with actigraphy data and a description of sleep behaviour as determined by an abbreviated …
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Characterization of the genetic variability of human arylalklamine-N-acetyltransferase (AA-NAT) and its potential effects on melatonin production and the sleep pattern
The human sleep/wake cycle is characterized by a circadian rhythm of circulating melatonin levels, which has been attributed to the cyclic expression of its biosynthetic rate-limiting enzyme, arylalkylamine-N-acetyl-transferase (AA-NAT). Genetic variability of the AA-NAT gene may therefore …